Concepedia

Pathway-based Repurposing

Pathway-Based Repurposing is a methodological framework in drug repurposing research that identifies novel therapeutic applications for existing compounds by systematically analyzing their effects on disease-associated biological pathways, distinguishing it from target- or phenotype-driven approaches through its focus on pathway-level modulation rather than individual molecular targets or observable traits.

12

Publications

453

Citations

77

Authors

36

Institutions

Publications per year

2017–2026

11

Parents

Publications

12

Bioinformatics methods in drug repurposing for Alzheimer’s disease

John C. Siavelis, Marilena M. Bourdakou, Emmanouil Athanasiadis et al. · Briefings in Bioinformatics · 2015 · 92 citations · Full text

, , +16

Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies

Namshik Han, Woochang Hwang, Konstantinos Tzelepis et al. · Science Advances · 2021 · 61 citations · Full text

, , +14

Pathway-Based Drug Repositioning for Breast Cancer Molecular Subtypes

Raúl A. Mejía-Pedroza, Jesús Espinal‐Enríquez, Enrique Hernández–Lemus · Frontiers in Pharmacology · 2018 · 50 citations · Full text

, , +17

Drug Repurposing: A Network-based Approach to Amyotrophic Lateral Sclerosis

Giulia Fiscon, Federica Conte, Susanna Amadio et al. · Neurotherapeutics · 2021 · 48 citations · Full text

, , +16

DrugRepo: a novel approach to repurposing drugs based on chemical and genomic features

Yinyin Wang, Jehad Aldahdooh, Yingying Hu et al. · Scientific Reports · 2022 · 44 citations · Full text

, , +17

1–5 of 12

Authors

77

  1. GL
    Guixia Liu

    East China University of Science and Technology, China

    1 publications · 18 citations

    1

    h-index

  2. MD
    Marina Díaz Uzquiano

    Universidad Politécnica de Madrid, Spain

    1 publications · 17 citations

    1

    h-index

  3. YW
    Yin‐Ying Wang

    The University of Texas Health Science Center at Houston, United States

    1 publications · 12 citations

    1

    h-index

  4. EY
    Eliza Yankova

    University of Cambridge, United Kingdom

    1 publications · 61 citations

    1

    h-index

  5. PK
    Pandikannan Krishnamoorthy

    Indian Institute of Science Education and Research, Bhopal, India

    1 publications · 36 citations

    1

    h-index

1–5 of 77

Institutions

36

  1. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    14 publications

    837 citations

  2. Telethon Institute Of Genetics And Medicine

    Naples, Italy

    1 h-index

    5 publications

    125 citations

  3. Bambino Gesù Children's Hospital

    Rome, Italy

    1 h-index

    7 publications

    175 citations

  4. The University of Osaka

    Osaka, Japan

    1 h-index

    1 publications

    36 citations

  5. Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti

    Rome, Italy

    1 h-index

    3 publications

    144 citations

  6. Centre for Plant Biotechnology and Genomics

    Pozuelo de Alarcón, Spain

    1 h-index

    1 publications

    17 citations

  7. LifeArc

    London, United Kingdom

    1 h-index

    1 publications

    61 citations

  8. Huazhong University of Science and Technology

    Wuhan, China

    1 h-index

    3 publications

    36 citations

1–8 of 36

Venues

  1. Frontiers in Pharmacology

    2 publications · 85 citations

    2

    h-index

  2. International Journal of Molecular Sciences

    IJMS · 1 publications · 25 citations

    1

    h-index

  3. Journal of Chemical Information and Modeling

    JCIM · 1 publications · 18 citations

    1

    h-index

  4. Oncotarget

    1 publications · 12 citations

    1

    h-index

  5. Computers in Biology and Medicine

    1 publications · 36 citations

    1

    h-index

1–5