Concepedia

Biomarker-guided Repurposing

Biomarker-Guided Repurposing is a drug repurposing strategy that systematically uses predictive molecular or clinical biomarkers to identify new therapeutic indications and responsive patient subpopulations for already approved drugs, particularly chemotherapeutic agents.

26

Publications

1.7K

Citations

211

Authors

111

Institutions

Publications per year

2017–2026

19

Parents

Children

Publications

26

Drug repurposing from an academic perspective

Tudor I. Oprea, Julie E. Bauman, Cristian Bologa et al. · Drug Discovery Today Therapeutic Strategies · 2011 · 369 citations

, , +10

Machine learning identifies candidates for drug repurposing in Alzheimer’s disease

Steve Rodriguez, Clemens B. Hug, Petar V. Todorov et al. · Nature Communications · 2021 · 297 citations · Full text

, , +17

Drug Repurposing: Far Beyond New Targets for Old Drugs

Tudor I. Oprea, Jordi Mestres · The AAPS Journal · 2012 · 291 citations · Full text

, , +16

Polypharmacology-based ceritinib repurposing using integrated functional proteomics

Brent M. Kuenzi, Lily L. Remsing Rix, Paul A. Stewart et al. · Nature Chemical Biology · 2017 · 96 citations · Full text

, , +14

Use of biomarkers from drug discovery through clinical practice: report of the Ninth European Federation of Pharmaceutical Sciences Conference on Optimizing Drug Development

Paul Rolan · Clinical Pharmacology & Therapeutics · 2003 · 80 citations

, , +16

1–5 of 26

Authors

211

  1. FZ
    Faı̈ez Zannad

    Inserm, France

    2 publications · 63 citations

    2

    h-index

  2. AA
    Adriaan A. Voors

    University Medical Center Groningen, Netherlands

    2 publications · 63 citations

    2

    h-index

  3. TI
    Tudor I. Oprea

    University of New Mexico, United States

    2 publications · 660 citations

    2

    h-index

  4. SD
    Stefan D. Anker

    Charité - Universitätsmedizin Berlin, Germany

    2 publications · 65 citations

    2

    h-index

  5. AW
    Angela Wandinger‐Ness

    University of New Mexico, United States

    1 publications · 369 citations

    1

    h-index

1–5 of 211

Institutions

111

  1. Universitätsmedizin Göttingen

    Göttingen, Germany

    3 h-index

    3 publications

    111 citations

  2. University of New Mexico

    Albuquerque, United States

    2 h-index

    27 publications

    9.9K citations

  3. Berlin Institute of Health at Charité - Universitätsmedizin Berlin

    Berlin, Germany

    2 h-index

    5 publications

    204 citations

  4. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    2 h-index

    14 publications

    514 citations

  5. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    2 publications

    660 citations

  6. Duke University

    Durham, United States

    2 h-index

    4 publications

    71 citations

  7. Berlin-Brandenburger Centrum für Regenerative Therapien

    Berlin, Germany

    2 h-index

    3 publications

    112 citations

  8. University of Groningen

    Groningen, The Netherlands

    2 h-index

    7 publications

    288 citations

1–8 of 111

Venues

  1. Nature Chemical Biology

    2 publications · 120 citations

    2

    h-index

  2. Journal of the American College of Cardiology

    JACC · 2 publications · 79 citations

    2

    h-index

  3. European Journal of Heart Failure

    2 publications · 66 citations

    2

    h-index

  4. Nature Communications

    1 publications · 297 citations

    2

    h-index

  5. Computers in Biology and Medicine

    1 publications · 36 citations

    2

    h-index

1–5