Concepedia

Pain Mediators

Pain Mediators is a class of endogenous biochemical substances that mediate the transmission and modulation of nociceptive signals during synovial inflammation by selectively activating specific receptors on sensory neurons and immune cells.

792

Publications

58.2K

Citations

3.9K

Authors

1K

Institutions

Publications per year

2017–2026

209

Parents

Publications

792

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

John B. Davis, Julie Gray, Martin J. Gunthorpe et al. · Nature · 2000 · 1.8K citations

, , +14

Different immune cells mediate mechanical pain hypersensitivity in male and female mice

Robert E. Sorge, Josiane C.S. Mapplebeck, Sarah F. Rosen et al. · Nature Neuroscience · 2015 · 1.4K citations · Full text

, , +15

p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia

Ru‐Rong Ji, Tarek A. Samad, Shan‐Xue Jin et al. · Neuron · 2002 · 1.2K citations · Full text

, , +15

Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances

Sun Wook Hwang, Hawon Cho, Jiyeon Kwak et al. · Proceedings of the National Academy of Sciences · 2000 · 1K citations

, , +17

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

Marcello Trevisani, Jan Siemens, Serena Materazzi et al. · Proceedings of the National Academy of Sciences · 2007 · 762 citations · Full text

, , +17

1–5 of 792

Authors

3.9K

  1. JJ
    Jason J. McDougall

    University of Calgary, Canada

    15 publications · 802 citations

    15

    h-index

  2. HU
    Hiroshi Ueda

    Nagasaki University, Japan

    11 publications · 1K citations

    11

    h-index

  3. HS
    Hans‐Georg Schaible

    Friedrich Schiller University Jena, Germany

    11 publications · 771 citations

    11

    h-index

  4. PW
    Peter W. Reeh

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    11 publications · 731 citations

    11

    h-index

  5. JD
    Jon D. Levine

    University of California, San Francisco, United States

    10 publications · 1.4K citations

    10

    h-index

1–5 of 3.9K

Institutions

1K

  1. Harvard University

    Cambridge, United States

    21 h-index

    93 publications

    15.8K citations

  2. University of Calgary

    Calgary, Canada

    20 h-index

    69 publications

    11.1K citations

  3. University of California, San Francisco

    San Francisco, United States

    19 h-index

    84 publications

    20.6K citations

  4. Universidade Federal de Santa Catarina

    Florianópolis, Brazil

    17 h-index

    45 publications

    2.3K citations

  5. Universidade de São Paulo

    São Paulo, Brazil

    17 h-index

    66 publications

    6.9K citations

  6. University of Würzburg

    Würzburg, Germany

    16 h-index

    51 publications

    3.3K citations

  7. King's College London

    London, United Kingdom

    15 h-index

    45 publications

    3.1K citations

  8. Stanford University

    Stanford, United States

    14 h-index

    49 publications

    3.5K citations

1–8 of 1K

Venues

  1. Pain

    62 publications · 6.3K citations

    42

    h-index

  2. Journal of Neuroscience

    28 publications · 5.1K citations

    27

    h-index

  3. Molecular Pain

    31 publications · 1.8K citations

    27

    h-index

  4. British Journal of Pharmacology

    BJP · 22 publications · 1.2K citations

    20

    h-index

  5. PubMed

    Repository · 29 publications · 1.3K citations

    19

    h-index

1–5