Different immune cells mediate mechanical pain hypersensitivity in male and female mice

Robert E. Sorge, Josiane C.S. Mapplebeck, Sarah F. Rosen, +18

Nature Neuroscience

InflammationAllergyHealth SciencesPain MedicineMedicine +9

p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia

Ru‐Rong Ji, Tarek A. Samad, Shan‐Xue Jin, +2

Neuron

InflammationPain ResearchAnti-inflammatoryMolecular PhysiologySignal Transduction +12

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1β, Interleukin-6, and Tumor Necrosis Factor-α in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

Yasuhiko Kawasaki, Ling Zhang, Jen‐Kun Cheng, +1

Journal of Neuroscience

p38 Mitogen-Activated Protein Kinase Is Activated after a Spinal Nerve Ligation in Spinal Cord Microglia and Dorsal Root Ganglion Neurons and Contributes to the Generation of Neuropathic Pain

Shan‐Xue Jin, Zhi-Ye Zhuang, Clifford J. Woolf, +1

Journal of Neuroscience

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity

Ru‐Rong Ji, Hiroshi Baba, Gary J. Brenner, +1

Nature Neuroscience

Pain SyndromeHealth SciencesNeurophysiologyPain MedicinePhysiology +11

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

Zhi‐Ye Zhuang, Peter Gerner, Clifford J. Woolf, +1

Pain

Pain MedicineErk KinaseNeuropathic PainMolecular PainDorsal Horn +16

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

Yasuhiko Kawasaki, Zhen‐Zhong Xu, Xiaoying Wang, +8

Nature Medicine

Pain SyndromePain MedicineMatrix MetalloproteasesNeuropathic PainPathology +10

Nociceptors Are Interleukin-1β Sensors

Alexander M. Binshtok, Haibin Wang, Katharina Zimmermann, +8

Journal of Neuroscience

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

Charles N. Serhan, Jesmond Dalli, Sergey Karamnov, +6

The FASEB Journal

Inflammatory Lung DiseaseImmunologyMolecular PainInnate ImmunityCellular Physiology +22

Resolvins RvE1 and RvD1 attenuate inflammatory pain via central and peripheral actions

Zhen‐Zhong Xu, Ling Zhang, Tong Liu, +5

Nature Medicine

InflammationAnti-inflammatoryHealth SciencesInflammatory PainPain Medicine +12