Jan Siemens

The menthol receptor TRPM8 is the principal detector of environmental cold

Diana M. Bautista, Jan Siemens, Joshua Glazer et al. · Nature · 2007 · 1.4K citations

Environmental Cold, Signal Transduction, Allergy +5

TRPA1 mediates formalin-induced pain

Colleen R. McNamara, Josh Mandel-Brehm, Diana M. Bautista et al. · Proceedings of the National Academy of Sciences · 2007 · 1.3K citations · Full text

Pain Medicine, Molecular Pain, Neurotransmission +19

4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1

Marcello Trevisani, Jan Siemens, Serena Materazzi et al. · Proceedings of the National Academy of Sciences · 2007 · 753 citations · Full text

Pain Medicine, Immunology, Neuropathic Pain +22

Cadherin 23 is a component of the tip link in hair-cell stereocilia

Jan Siemens, Concepción Lillo, Rachel A. Dumont et al. · Nature · 2004 · 485 citations

Developmental Biology, Cell Interaction, Molecular Biology +8

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

Kun Song, Hong Wang, Gretel B. Kamm et al. · Science · 2016 · 403 citations · Full text

Trp Channels, Homeostatic Mechanism, Thermal Therapy +18