Concepedia

Overdose Toxicity

Overdose Toxicity is a pharmacological phenomenon characterized by the acute physiological and neurological impairment resulting from the excessive intake of sedative-hypnotic drugs, leading to central nervous system depression that exceeds therapeutic efficacy and manifests in potentially fatal respiratory and cardiovascular compromise.

1.2K

Publications

46.4K

Citations

3.8K

Authors

1.2K

Institutions

Publications per year

2017–2026

113

Parents

Publications

1.2K

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

Mitchell R. McGill, Matthew R. Sharpe, C. David Williams et al. · Journal of Clinical Investigation · 2012 · 763 citations · Full text

, , +17

Benzodiazepine prescribing patterns and deaths from drug overdose among US veterans receiving opioid analgesics: case-cohort study

Tae Woo Park, R Saitz, Dara Ganoczy et al. · BMJ · 2015 · 580 citations · Full text

, , +16

Acute liver necrosis following overdose of paracetamol.

Diana Davidson, W. N. Eastham · BMJ · 1966 · 534 citations · Full text

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Relative Toxicity of Selective Serotonin Reuptake Inhibitors (SSRIs) in Overdose

Geoffrey K. Isbister, Steven J. Bowe, Andrew Dawson et al. · Journal of Toxicology Clinical Toxicology · 2004 · 434 citations · Full text

, , +14

Relative mortality from overdose of antidepressants

John A. Henry, Carol Alexander, Ersin K. Sener · BMJ · 1995 · 292 citations · Full text

, , +16

1–5 of 1.2K

Authors

3.8K

  1. GK
    Geoffrey K. Isbister

    University of Newcastle Australia, Australia

    28 publications · 1.7K citations

    23

    h-index

  2. RS
    Robert S. Hoffman

    New York University, United States

    14 publications · 553 citations

    13

    h-index

  3. IM
    Ian M. Whyte

    University of Newcastle Australia, Australia

    11 publications · 1.4K citations

    11

    h-index

  4. EP
    Edward P. Krenzelok

    Children's Hospital of Pittsburgh, United States

    10 publications · 431 citations

    10

    h-index

  5. BL
    Barry Levine

    Office of Chief Medical Examiner, United States

    9 publications · 367 citations

    9

    h-index

1–5 of 3.8K

Institutions

1.2K

  1. Washington Poison Center

    Seattle, United States

    32 h-index

    123 publications

    6.2K citations

  2. University of Newcastle Australia

    Newcastle, Australia

    20 h-index

    40 publications

    2.4K citations

  3. University of Colorado Denver

    Denver, United States

    18 h-index

    37 publications

    1.9K citations

  4. Calvary Mater Newcastle Hospital

    Waratah, Australia

    16 h-index

    28 publications

    1.3K citations

  5. Office of Chief Medical Examiner

    New York, United States

    15 h-index

    64 publications

    2.5K citations

  6. University of California, San Francisco

    San Francisco, United States

    14 h-index

    51 publications

    3.3K citations

  7. Edinburgh Royal Infirmary

    Edinburgh, United Kingdom

    13 h-index

    43 publications

    2.1K citations

  8. Mater Misericordiae Hospital

    Townsville, Australia

    12 h-index

    28 publications

    3.8K citations

1–8 of 1.2K

Venues

  1. Journal of Toxicology Clinical Toxicology

    67 publications · 3.2K citations

    35

    h-index

  2. PubMed

    Repository · 125 publications · 3.8K citations

    33

    h-index

  3. Clinical Toxicology

    62 publications · 2.5K citations

    31

    h-index

  4. Journal of Analytical Toxicology

    JAT · 49 publications · 1.8K citations

    27

    h-index

  5. Journal of Forensic Sciences

    JOFS · 39 publications · 1.6K citations

    23

    h-index

1–5