Matthew R. Sharpe

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

Mitchell R. McGill, Matthew R. Sharpe, C. David Williams et al. · Journal of Clinical Investigation · 2012 · 763 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

Daniel J. Antoine, Rosalind E. Jenkins, James W. Dear et al. · Journal of Hepatology · 2012 · 307 citations

Veterinary Medicine, Biomedical Sciences, Pharmacology +16

Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome

Mitchell R. McGill, Vincent S. Staggs, Matthew R. Sharpe et al. · Hepatology · 2014 · 183 citations · Full text

Pharmacy, Clinical Toxicology, Toxicology +17

Neutrophil activation during acetaminophen hepatotoxicity and repair in mice and humans

C. David Williams, Mary Lynn Bajt, Matthew R. Sharpe et al. · Toxicology and Applied Pharmacology · 2014 · 169 citations

Veterinary Medicine, Immunology, Pharmacology +14

Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humans

Mitchell R. McGill, Feng Li, Matthew R. Sharpe et al. · Archives of Toxicology · 2013 · 145 citations · Full text

Pharmacy, Pharmacology, Toxicology +12