Mitchell R. McGill

The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

Mitchell R. McGill, Matthew R. Sharpe, C. David Williams et al. · Journal of Clinical Investigation · 2012 · 732 citations · Full text

Mitochondrial Dysfunction, Cell Death, Pathology +19

Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity

Mitchell R. McGill, C. David Williams, Yuchao Xie et al. · Toxicology and Applied Pharmacology · 2012 · 412 citations · Full text

Hepatology, Biochemistry, Mitochondrial Dysfunction +9

RETRACTED: Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

Daniel J. Antoine, Rosalind E. Jenkins, James W. Dear et al. · Journal of Hepatology · 2012 · 306 citations · Full text

Hepatology, Mechanistic Biomarkers, Medicine +8

HepaRG Cells: A Human Model to Study Mechanisms of Acetaminophen Hepatotoxicity Δσ

Mitchell R. McGill, Huimin Yan, Anup Ramachandran et al. · Hepatology · 2010 · 285 citations · Full text

Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice

Anup Ramachandran, Mitchell R. McGill, Yuchao Xie et al. · Hepatology · 2013 · 260 citations · Full text