Concepedia

Origin Firing Control

Origin Firing Control is a regulatory mechanism in the eukaryotic cell cycle that governs the activation of DNA replication origins to ensure precise and coordinated initiation of DNA synthesis while preventing re-replication and maintaining genomic stability.

84

Publications

6.2K

Citations

385

Authors

166

Institutions

Publications per year

2017–2026

21

Variants

Origin Firing Regulation

Parents

Publications

84

Regulated eukaryotic DNA replication origin firing with purified proteins

Joseph T.P. Yeeles, Tom Deegan, Agnieszka Janska et al. · Nature · 2015 · 530 citations · Full text

, , +12

ATR and ATM regulate the timing of DNA replication origin firing

David Shechter, Vincenzo Costanzo, Jean Gautier · Nature Cell Biology · 2004 · 377 citations

, , +12

Chk1 promotes replication fork progression by controlling replication initiation

Eva Petermann, Mick Woodcock, Thomas Helleday · Proceedings of the National Academy of Sciences · 2010 · 304 citations · Full text

, , +17

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

Seiji Tanaka, Ryuichiro Nakato, Yuki Katou et al. · Current Biology · 2011 · 261 citations · Full text

, , +9

Visualization of Altered Replication Dynamics after DNA Damage in Human Cells

Catherine J. Merrick, Dean A. Jackson, John F.X. Diffley · Journal of Biological Chemistry · 2004 · 231 citations · Full text

, , +17

1–5 of 84

Authors

385

  1. JL
    Joyce L. Hamlin

    University of Virginia, United States

    4 publications · 192 citations

    4

    h-index

  2. OH
    Olivier Hyrien

    Centre National de la Recherche Scientifique, France

    3 publications · 203 citations

    3

    h-index

  3. AB
    Aaron Bensimon

    Institut Pasteur, France

    3 publications · 305 citations

    3

    h-index

  4. MR
    Maya Raghunandan

    University of Minnesota, United States

    3 publications · 158 citations

    3

    h-index

  5. JF
    John F.X. Diffley

    The Francis Crick Institute, United Kingdom

    3 publications · 800 citations

    3

    h-index

1–5 of 385

Institutions

166

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    28 publications

    914 citations

  2. University of Massachusetts Chan Medical School

    Worcester, United States

    5 h-index

    9 publications

    969 citations

  3. Cancer Research UK

    London, United Kingdom

    4 h-index

    11 publications

    3K citations

  4. University of Virginia

    Charlottesville, United States

    4 h-index

    12 publications

    570 citations

  5. Inserm

    Paris, France

    4 h-index

    15 publications

    495 citations

  6. Tokyo Metropolitan Institute of Medical Science

    Tokyo, Japan

    3 h-index

    18 publications

    470 citations

  7. Institut de Génétique Humaine

    Montpellier, France

    3 h-index

    8 publications

    396 citations

  8. University of Duisburg-Essen

    Essen, Germany

    3 h-index

    11 publications

    238 citations

1–8 of 166

Venues

  1. Molecular and Cellular Biology

    MCB · 8 publications · 425 citations

    8

    h-index

  2. Cell Cycle

    7 publications · 332 citations

    7

    h-index

  3. Nucleic Acids Research

    6 publications · 197 citations

    6

    h-index

  4. Cell

    5 publications · 381 citations

    5

    h-index

  5. Molecular Biology of the Cell

    MBC · 5 publications · 456 citations

    5

    h-index

1–5