Concepedia

Opioid Antagonists

Opioid Antagonist is a pharmacological agent that competitively inhibits opioid receptor activation by binding to opioid receptors without producing intrinsic activity, thereby reversing or blocking the effects of opioid agonists.

1.4K

Publications

74K

Citations

4.4K

Authors

1.1K

Institutions

Publications per year

2017–2026

99

Variants

Opioid Antagonist

Parents

Publications

1.4K

Opiate Receptor: Demonstration in Nervous Tissue

Candace B. Pert, Solomon H. Snyder · Science · 1973 · 2.4K citations

, , +10

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Aashish Manglik, Andrew C. Kruse, Tong Sun Kobilka et al. · Nature · 2012 · 1.4K citations

, , +14

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

Charles Chavkin, Iain F. James, Avram Goldstein · Science · 1982 · 1.2K citations

, , +17

Opioid analgesics and antagonists

Terry Reisine · Medical Entomology and Zoology · 1996 · 1.2K citations

, , +12

Basic opioid pharmacology: an update

Hasan Pathan, John P. Williams · British Journal of Pain · 2012 · 670 citations · Full text

, , +17

1–5 of 1.4K

Authors

4.4K

  1. PS
    Philip S. Portoghese

    University of Minnesota, United States

    52 publications · 5.2K citations

    33

    h-index

  2. AT
    A.E. Takemori

    University of Minnesota, United States

    44 publications · 4.8K citations

    31

    h-index

  3. PW
    Peter W. Schiller

    Montreal Clinical Research Institute, Canada

    28 publications · 1.3K citations

    20

    h-index

  4. SS
    Severo Salvadori

    University of Ferrara, Italy

    24 publications · 964 citations

    18

    h-index

  5. HN
    Hiroshi Nagase

    Toray Industries, Inc. (Japan), Japan

    22 publications · 1.5K citations

    18

    h-index

1–5 of 4.4K

Institutions

1.1K

  1. University of Minnesota

    Minneapolis, United States

    39 h-index

    170 publications

    15.3K citations

  2. University of Michigan

    Ann Arbor, United States

    28 h-index

    209 publications

    9.4K citations

  3. University of Arizona

    Tucson, United States

    26 h-index

    219 publications

    12.9K citations

  4. Twin Cities Orthopedics

    Edina, United States

    24 h-index

    56 publications

    7.9K citations

  5. National Institute on Drug Abuse

    Bethesda, United States

    22 h-index

    120 publications

    5.1K citations

  6. National Institutes of Health

    Bethesda, United States

    21 h-index

    116 publications

    6K citations

  7. Eli Lilly (United States)

    Indianapolis, United States

    20 h-index

    195 publications

    7.8K citations

  8. RTI International

    Durham, United States

    19 h-index

    166 publications

    6.9K citations

1–8 of 1.1K

Venues

  1. 52

    h-index

  2. Journal of Medicinal Chemistry

    128 publications · 6.7K citations

    46

    h-index

  3. European Journal of Pharmacology

    EJP · 64 publications · 3.5K citations

    33

    h-index

  4. PubMed

    Repository · 80 publications · 3.5K citations

    32

    h-index

  5. Brain Research

    39 publications · 1.7K citations

    28

    h-index

1–5