Concepedia

Off-target Toxicity Reduction

Off-Target Toxicity Reduction is a methodological framework in toxicology and pharmacology that specifically targets the minimization of adverse biological effects caused by unintended interactions of therapeutic agents with non-disease-related molecular pathways or cellular components.

148

Publications

8.5K

Citations

1.4K

Authors

384

Institutions

Publications per year

2017–2026

124

Parents

Publications

148

Various methods of gold nanoparticles (GNPs) conjugation to antibodies

Hamed Amani, Ali Akbar Pourfatollah, Hamidreza Pazoki–Toroudi et al. · Sensing and Bio-Sensing Research · 2016 · 532 citations · Full text

, , +17

Local bacteria affect the efficacy of chemotherapeutic drugs

Panos Lehouritis, Joanne Cummins, Michael Stanton et al. · Scientific Reports · 2015 · 304 citations · Full text

, , +17

Reversible Spatiotemporal Control of Induced Protein Degradation by Bistable PhotoPROTACs

Patrick Pfaff, Kusal T. G. Samarasinghe, Craig M. Crews et al. · ACS Central Science · 2019 · 292 citations · Full text

, , +17

The Role of Matrix Metalloproteinases in Colorectal Cancer

Anan Said, Jean‐Pierre Raufman, Guofeng Xie · Cancers · 2014 · 227 citations · Full text

, , +16

Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma

Tseng Hsiang-Chi, Wei Xiong, Saiaditya Badeti et al. · Nature Communications · 2020 · 212 citations · Full text

, , +17

1–5 of 148

Authors

1.4K

  1. ME
    Meredith E. Jackrel

    University of Pennsylvania, United States

    2 publications · 57 citations

    2

    h-index

  2. XZ
    Xiaoyan Zhang

    Shanghai Public Health Clinical Center, China

    2 publications · 78 citations

    2

    h-index

  3. AA
    Antonella Adami

    Charing Cross Hospital, United Kingdom

    2 publications · 92 citations

    2

    h-index

  4. SR
    Sandro R. P. da Rocha

    Wayne State University, United States

    2 publications · 71 citations

    2

    h-index

  5. MK
    Motoichi Kurisawa

    Institute of Bioengineering and Nanotechnology, Singapore

    2 publications · 201 citations

    2

    h-index

1–5 of 1.4K

Institutions

384

  1. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    58 publications

    2.9K citations

  2. University of Science and Technology of China

    Hefei, China

    5 h-index

    29 publications

    982 citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    4 h-index

    16 publications

    881 citations

  4. Shanghai Institute of Materia Medica

    Pudong, China

    4 h-index

    25 publications

    1.2K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    4 h-index

    20 publications

    2K citations

  6. Sichuan University

    Chengdu, China

    4 h-index

    26 publications

    862 citations

  7. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    25 publications

    1.2K citations

  8. Beckman Research Institute

    Duarte, United States

    3 h-index

    15 publications

    354 citations

1–8 of 384

Venues

  1. ACS Applied Materials & Interfaces

    8 publications · 466 citations

    8

    h-index

  2. Molecular Cancer Therapeutics

    MCT · 8 publications · 475 citations

    8

    h-index

  3. ACS Nano

    6 publications · 351 citations

    6

    h-index

  4. Molecular Pharmaceutics

    5 publications · 279 citations

    5

    h-index

  5. Nature Communications

    4 publications · 497 citations

    4

    h-index

1–5