Concepedia

Nucleotide Analogs

Nucleotide Analogs is a modified nucleotide derivative in which the natural purine or pyrimidine base, sugar moiety, or phosphate group is altered to serve therapeutic, diagnostic, or investigative functions while retaining the capacity to participate in nucleic acid synthesis or binding.

1.5K

Publications

69.5K

Citations

5.1K

Authors

1.1K

Institutions

Publications per year

2017–2026

110

Variants

Nucleotide Analogues

Parents

Publications

1.5K

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

Stanley Tabor, C C Richardson · Proceedings of the National Academy of Sciences · 1987 · 2.3K citations · Full text

, , +16

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

Pennina R. Langer, Alex A. Waldrop, David C. Ward · Proceedings of the National Academy of Sciences · 1981 · 1.1K citations · Full text

, , +17

The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

Calvin J. Gordon, Egor P. Tchesnokov, Joy Y. Feng et al. · Journal of Biological Chemistry · 2020 · 890 citations · Full text

, , +17

Peptide nucleic acids (PNA). Oligonucleotide analogs with an achiral peptide backbone

Ole Buchardt, Peter E. Nielsen, Rolf H. Berg · Journal of the American Chemical Society · 1992 · 736 citations

, , +12

Potent and nontoxic antisense oligonucleotides containing locked nucleic acids

Claes Wahlestedt, Peter Salmi, Liam Good et al. · Proceedings of the National Academy of Sciences · 2000 · 620 citations

, , +14

1–5 of 1.5K

Authors

5.1K

  1. ED
    Erik De Clercq

    Rega Institute for Medical Research, Belgium

    32 publications · 2.8K citations

    23

    h-index

  2. JB
    Jan Balzarini

    Rega Institute for Medical Research, Belgium

    24 publications · 1.6K citations

    19

    h-index

  3. NO
    Nathan O. Kaplan

    Brandeis University, United States

    18 publications · 1.6K citations

    16

    h-index

  4. CM
    Chris Meier

    Universität Hamburg, Germany

    14 publications · 779 citations

    14

    h-index

  5. CM
    Christopher McGuigan

    Cardiff University, United Kingdom

    15 publications · 789 citations

    14

    h-index

1–5 of 5.1K

Institutions

1.1K

  1. Rega Institute for Medical Research

    Leuven, Belgium

    28 h-index

    163 publications

    9.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    238 publications

    8K citations

  3. KU Leuven

    Leuven, Belgium

    24 h-index

    123 publications

    5.3K citations

  4. National Institutes of Health

    Bethesda, United States

    21 h-index

    95 publications

    4.4K citations

  5. Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

    Prague, Czechia

    20 h-index

    130 publications

    5.7K citations

  6. Gilead Sciences (United States)

    Foster City, United States

    18 h-index

    120 publications

    9.2K citations

  7. Yale University

    New Haven, United States

    16 h-index

    55 publications

    6.1K citations

  8. National Cancer Institute

    Bethesda, United States

    15 h-index

    47 publications

    2.5K citations

1–8 of 1.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 92 publications · 7.6K citations

    49

    h-index

  2. Nucleic Acids Research

    65 publications · 2.9K citations

    34

    h-index

  3. Journal of Medicinal Chemistry

    71 publications · 3.8K citations

    34

    h-index

  4. Biochemistry

    58 publications · 2.9K citations

    33

    h-index

  5. Journal of the American Chemical Society

    JACS · 40 publications · 3.9K citations

    30

    h-index

1–5