Concepedia

Mutation Hotspot Analysis

Mutation Hotspot Analysis is a computational method in mutation analysis that identifies and characterizes genomic regions with a significantly higher frequency of mutations compared to surrounding sequences, enabling the detection of functionally relevant sites implicated in disease or evolutionary processes.

204

Publications

11.3K

Citations

1.8K

Authors

598

Institutions

Publications per year

2017–2026

66

Parents

Publications

204

Oncogenic Mutations of PIK3CA in Human Cancers

Yardena Samuels, Victor E. Velculescu · Cell Cycle · 2004 · 532 citations · Full text

, , +17

PMUT: a web-based tool for the annotation of pathological mutations on proteins

Carles Ferrer‐Costa, Josep Lluis Gelpí, L. Zamakola et al. · Computer applications in the biosciences · 2005 · 502 citations · Full text

, , +17

Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials

Funda Meric‐Bernstam, Lauren Brusco, Kenna Shaw et al. · Journal of Clinical Oncology · 2015 · 430 citations · Full text

, , +17

Clinical Validation of a Next-Generation Sequencing Screen for Mutational Hotspots in 46 Cancer-Related Genes

Rajesh R. Singh, Keyur P. Patel, Mark J. Routbort et al. · Journal of Molecular Diagnostics · 2013 · 313 citations · Full text

, , +17

Comprehensive omic characterization of breast cancer in Mexican-Hispanic women

Sandra Romero‐Córdoba, Iván Salido-Guadarrama, Rosa Rebollar‐Vega et al. · Nature Communications · 2021 · 291 citations · Full text

, , +17

1–5 of 204

Authors

1.8K

  1. MJ
    Mark J. Routbort

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 756 citations

    3

    h-index

  2. SK
    Scott Kopetz

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 484 citations

    3

    h-index

  3. CH
    Christian Hafner

    University of Regensburg, Germany

    3 publications · 108 citations

    3

    h-index

  4. FM
    Funda Meric‐Bernstam

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 484 citations

    3

    h-index

  5. DM
    David M. DeMarini

    Environmental Protection Agency, United States

    3 publications · 137 citations

    3

    h-index

1–5 of 1.8K

Institutions

598

  1. Memorial Sloan Kettering Cancer Center

    New York, United States

    9 h-index

    64 publications

    3.6K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    8 h-index

    78 publications

    13.1K citations

  3. Inserm

    Paris, France

    7 h-index

    40 publications

    3K citations

  4. Heidelberg University

    Heidelberg, Germany

    6 h-index

    17 publications

    768 citations

  5. National Cancer Institute

    Bethesda, United States

    5 h-index

    23 publications

    3K citations

  6. German Cancer Research Center

    Heidelberg, Germany

    5 h-index

    13 publications

    584 citations

  7. University of Regensburg

    Regensburg, Germany

    5 h-index

    10 publications

    317 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    7 publications

    350 citations

1–8 of 598

Venues

  1. Human Mutation

    8 publications · 378 citations

    8

    h-index

  2. PubMed

    Repository · 7 publications · 149 citations

    7

    h-index

  3. PLoS ONE

    6 publications · 299 citations

    6

    h-index

  4. Carcinogenesis

    6 publications · 533 citations

    6

    h-index

  5. Human Molecular Genetics

    5 publications · 291 citations

    5

    h-index

1–5