Concepedia

Mutation Frequency Optimization

Mutation Frequency Optimization is a methodological framework in mutagenesis research that systematically adjusts mutagen dosage and exposure conditions to achieve a targeted mutation rate, distinguishing it from related approaches by its focus on maximizing phenotypic diversity while minimizing lethal mutations.

18

Publications

959

Citations

86

Authors

30

Institutions

Publications per year

2017–2026

7

Parents

Publications

18

Development of potent in vivo mutagenesis plasmids with broad mutational spectra

Ahmed H. Badran, David R. Liu · Nature Communications · 2015 · 214 citations · Full text

, , +15

Efficient random mutagenesis method with adjustable mutation frequency by use of PCR and dITP

Johan H. Spee, Willem M. de Vos, Oscar P. Kuipers · Nucleic Acids Research · 1993 · 162 citations · Full text

, , +11

Optimizing TILLING populations for reverse genetics in <i>Medicago truncatula</i>

Christine Le Signor, Vincent Savois, Grégoire Aubert et al. · Plant Biotechnology Journal · 2009 · 106 citations

, , +14

A Model for Designing Adaptive Laboratory Evolution Experiments

Ryan A. LaCroix, Bernhard Ø. Palsson, Adam M. Feist · Applied and Environmental Microbiology · 2017 · 104 citations · Full text

, , +14

Directed evolution of polypropylene and polystyrene binding peptides

Kristin Rübsam, Lina Weber, Felix Jakob et al. · Biotechnology and Bioengineering · 2017 · 68 citations

, , +14

1–5 of 18

Authors

86

  1. US
    Ulrich Schwaneberg

    RWTH Aachen University, Germany

    2 publications · 95 citations

    2

    h-index

  2. CM
    Christopher Moore

    Yale University, United States

    1 publications · 41 citations

    1

    h-index

  3. GW
    Guixing Wang

    Chinese Academy of Fishery Sciences, China

    1 publications · 16 citations

    1

    h-index

  4. LW
    Liyan Wang

    Nihon University, Japan

    1 publications · 16 citations

    1

    h-index

  5. MM
    Maode Ma

    Nanyang Technological University, Singapore

    1 publications · 18 citations

    1

    h-index

1–5 of 86

Institutions

30

  1. Novo Nordisk Foundation

    Copenhagen, Denmark

    2 h-index

    5 publications

    295 citations

  2. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    5 publications

    295 citations

  3. Universidad de Santiago de Chile

    Santiago, Chile

    1 h-index

    5 publications

    85 citations

  4. Sapienza University of Rome

    Rome, Italy

    1 h-index

    2 publications

    72 citations

  5. Kyoto University

    Kyoto, Japan

    1 h-index

    2 publications

    26 citations

  6. Harvard University

    Cambridge, United States

    1 h-index

    2 publications

    428 citations

  7. Tsinghua University

    Beijing, China

    1 h-index

    1 publications

    16 citations

  8. BASF (Germany)

    Ludwigshafen am Rhein, Germany

    1 h-index

    1 publications

    27 citations

1–8 of 30

Venues

  1. Nucleic Acids Research

    2 publications · 203 citations

    2

    h-index

  2. Applied and Environmental Microbiology

    AEM · 2 publications · 137 citations

    2

    h-index

  3. Human Mutation

    1 publications · 36 citations

    1

    h-index

  4. ACS Synthetic Biology

    1 publications · 29 citations

    1

    h-index

  5. Genetics

    1 publications · 20 citations

    1

    h-index

1–5