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Efficient random mutagenesis method with adjustable mutation frequency by use of PCR and dITP

Johan H. Spee, Willem M. de Vos, Oscar P. Kuipers

Nucleic Acids Research · 1993 · 162 citations · 4 references

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Abstract

Johan H. Spee, Willem M. de Vos, Oscar P Kuipers; Efficient random mutagenesis method with adjustable mutation frequency by use of PCR and dITP, Nucleic Acids R

References

4

DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA.

Michael A. Innis, K B Myambo, David H. Gelfand et al. · Proceedings of the National Academy of Sciences · 1988 · 779 citations · Full text

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Identification and characterization of the lantibiotic nisin Z, a natural nisin variant

John W. M. Mulders, I.J. Boerrigter, Harry S. Rollema et al. · European Journal of Biochemistry · 1991 · 435 citations · Full text

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Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase

Yuhong Zhou, X P Zhang, Richard H. Ebright · Nucleic Acids Research · 1991 · 239 citations · Full text

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Improved site-directed mutagenesis method using PCR

Oscar P. Kuipers, Hein J. Boot, Willem M. de Vos · Nucleic Acids Research · 1991 · 118 citations · Full text

, , +9