Concepedia

Model-based Differential Expression

Model-Based Differential Expression is a computational approach that belongs to the class of differential expression analysis methods and is distinguished by its reliance on statistical or mathematical models to infer changes in gene expression levels between conditions while accounting for biological and technical variability.

69

Publications

8.9K

Citations

242

Authors

147

Institutions

Publications per year

2017–2026

10

Parents

Publications

69

Differential analysis of RNA-seq incorporating quantification uncertainty

Harold Pimentel, Nicolas Bray, Suzette Puente et al. · Nature Methods · 2017 · 1.7K citations · Full text

, , +13

Bayesian approach to single-cell differential expression analysis

Peter V. Kharchenko, Lev Silberstein, David T. Scadden · Nature Methods · 2014 · 1.5K citations · Full text

, , +14

A comparison of background correction methods for two-colour microarrays

Matthew E. Ritchie, Jeremy D. Silver, Alicia Oshlack et al. · Bioinformatics · 2007 · 933 citations · Full text

, , +14

Analyzing gene expression data in terms of gene sets: methodological issues

Jelle J. Goeman, Peter Bühlmann · Bioinformatics · 2007 · 833 citations · Full text

, , +15

Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data

Trey Ideker, Vésteinn Thórsson, Andrew F. Siegel et al. · Journal of Computational Biology · 2000 · 325 citations

, , +14

1–5 of 69

Authors

242

  1. JM
    James M. Olson

    Fred Hutch Cancer Center, United States

    2 publications · 331 citations

    2

    h-index

  2. PS
    Pamela Swain

    NKT Therapeutics (United States), United States

    2 publications · 139 citations

    2

    h-index

  3. GK
    Gordon K. Smyth

    Walter and Eliza Hall Institute of Medical Research, Australia

    2 publications · 1.1K citations

    2

    h-index

  4. JB
    Jane B. Lian

    University of Massachusetts Chan Medical School, United States

    2 publications · 139 citations

    2

    h-index

  5. MA
    Michael Artinger

    University of California, Irvine, United States

    2 publications · 139 citations

    2

    h-index

1–5 of 242

Institutions

147

  1. University of California, Berkeley

    Berkeley, United States

    4 h-index

    11 publications

    5.8K citations

  2. Fred Hutch Cancer Center

    Seattle, United States

    3 h-index

    10 publications

    1.4K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    4 publications

    459 citations

  4. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    9 publications

    6.6K citations

  5. University of Iceland

    Reykjavik, Iceland

    2 h-index

    2 publications

    1.8K citations

  6. University of British Columbia

    Vancouver, Canada

    2 h-index

    3 publications

    317 citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    2 h-index

    10 publications

    702 citations

  8. Imperial College London

    London, United Kingdom

    2 h-index

    4 publications

    293 citations

1–8 of 147

Venues

  1. Bioinformatics

    7 publications · 2.3K citations

    7

    h-index

  2. BMC Bioinformatics

    6 publications · 370 citations

    6

    h-index

  3. Journal of Computational Biology

    3 publications · 523 citations

    3

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 3 publications · 147 citations

    3

    h-index

  5. Journal of Cellular Biochemistry

    2 publications · 139 citations

    2

    h-index

1–5