Concepedia

Microsomal Enzyme Activity

Microsomal Enzyme Activity is a biochemical phenomenon defined as the catalytic function of enzymes localized in the endoplasmic reticulum, particularly cytochrome P450 isoforms, that mediate the biotransformation of xenobiotics and endogenous substrates through oxidative reactions.

2.1K

Publications

112.9K

Citations

5.7K

Authors

1.1K

Institutions

Publications per year

2017–2026

27

Parents

Publications

2.1K

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

Daniel W. Nebert, Harry V. Gelboin · Journal of Biological Chemistry · 1968 · 1.7K citations · Full text

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ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

Henri Beaufay, A Amar-Costesec, Ernest Feytmans et al. · The Journal of Cell Biology · 1974 · 837 citations · Full text

, , +15

Hepatic Microsomal Ethanol-oxidizing System

Charles S. Lieber, Leonore M. DeCarli · Journal of Biological Chemistry · 1970 · 819 citations · Full text

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ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER

Lars Ernster, Philip Siekevitz, George E. Palade · The Journal of Cell Biology · 1962 · 712 citations · Full text

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Role of Hemoprotein P-450 in Fatty Acid ω-Hydroxylation in a Soluble Enzyme System from Liver Microsomes

Albert Lu, M J Coon · Journal of Biological Chemistry · 1968 · 627 citations · Full text

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1–5 of 2.1K

Authors

5.7K

  1. CD
    Curtis D. Klaassen

    University of Kansas Medical Center, United States

    27 publications · 1.7K citations

    25

    h-index

  2. WL
    Wayne Levin

    La Roche College, United States

    26 publications · 2K citations

    22

    h-index

  3. FO
    Franz Oesch

    Johannes Gutenberg University Mainz, Germany

    28 publications · 1.3K citations

    19

    h-index

  4. JR
    James R. Fouts

    University of Iowa, United States

    17 publications · 790 citations

    16

    h-index

  5. FP
    F. Peter Guengerich

    Vanderbilt University, United States

    14 publications · 1.3K citations

    13

    h-index

1–5 of 5.7K

Institutions

1.1K

  1. National Institutes of Health

    Bethesda, United States

    31 h-index

    137 publications

    13.9K citations

  2. Karolinska Institutet

    Stockholm, Sweden

    29 h-index

    117 publications

    11.8K citations

  3. University of Kansas Medical Center

    Kansas City, United States

    26 h-index

    72 publications

    4.1K citations

  4. La Roche College

    Pittsburgh, United States

    23 h-index

    85 publications

    8.9K citations

  5. University of Michigan

    Ann Arbor, United States

    21 h-index

    65 publications

    9.2K citations

  6. National Cancer Institute

    Bethesda, United States

    21 h-index

    80 publications

    8.9K citations

  7. University of Wisconsin–Madison

    Madison, United States

    21 h-index

    56 publications

    3.7K citations

  8. Harvard University

    Cambridge, United States

    20 h-index

    65 publications

    3.5K citations

1–8 of 1.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 192 publications · 20.7K citations

    78

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  2. PubMed

    Repository · 185 publications · 7.7K citations

    45

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  3. 39

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 60 publications · 4.4K citations

    35

    h-index

  5. Drug Metabolism and Disposition

    74 publications · 4.7K citations

    34

    h-index

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