Curtis D. Klaassen

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.4K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +13

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

Bo Kong, Li Wang, John Y.L. Chiang et al. · Hepatology · 2012 · 444 citations

Life Sciences, Molecular Biology, Pharmacology +16

Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption

Kai Wu, Julia Yue Cui, Curtis D. Klaassen · Toxicological Sciences · 2011 · 364 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor-E2–related factor-2 transcriptional pathway

Jonathan Maher, Matthew Z. Dieter, Lauren M. Aleksunes et al. · Hepatology · 2007 · 312 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Cadmium-induced hepatic and renal injury in chronically exposed rats: Likely role of hepatic cadmium-metallothionein in nephrotoxicity

Robert E. Dudley, Lynda M. Gammal, Curtis D. Klaassen · Toxicology and Applied Pharmacology · 1985 · 277 citations

Pharmacy, Nephrology, Toxicology +16