Concepedia

Mechanism-based Repurposing

Mechanism-Based Repurposing is a systematic drug discovery strategy that identifies new therapeutic applications for existing drugs by leveraging a deep understanding of their molecular mechanisms of action.

291

Publications

15.9K

Citations

2.1K

Authors

788

Institutions

Publications per year

2017–2026

216

Parents

Children

Publications

291

Coronavirus puts drug repurposing on the fast track

Charlotte Harrison · Nature Biotechnology · 2020 · 511 citations

, , +12

Auranofin: Repurposing an Old Drug for a Golden New Age

Christine Röder, Melanie J. Thomson · Drugs in R&D · 2015 · 499 citations · Full text

, , +9

In silico studies on therapeutic agents for COVID-19: Drug repurposing approach

Bhumi Shah, Palmi Modi, Sneha R. Sagar · Life Sciences · 2020 · 424 citations · Full text

, , +14

The NCGC Pharmaceutical Collection: A Comprehensive Resource of Clinically Approved Drugs Enabling Repurposing and Chemical Genomics

Ruili Huang, Noel Southall, Yuhong Wang et al. · Science Translational Medicine · 2011 · 412 citations

, , +17

Drug repurposing from an academic perspective

Tudor I. Oprea, Julie E. Bauman, Cristian Bologa et al. · Drug Discovery Today Therapeutic Strategies · 2011 · 369 citations

, , +10

1–5 of 291

Authors

2.1K

  1. MS
    Min Shen

    National Center for Advancing Translational Sciences, United States

    5 publications · 473 citations

    5

    h-index

  2. TI
    Tudor I. Oprea

    University of New Mexico, United States

    4 publications · 826 citations

    4

    h-index

  3. LX
    Lei Xie

    Hunter College, United States

    4 publications · 356 citations

    4

    h-index

  4. PS
    Paul Shinn

    National Institutes of Health, United States

    4 publications · 624 citations

    4

    h-index

  5. WZ
    Wei Zheng

    National Institutes of Health, United States

    4 publications · 386 citations

    4

    h-index

1–5 of 2.1K

Institutions

788

  1. Harvard University

    Cambridge, United States

    14 h-index

    51 publications

    7.6K citations

  2. Stanford University

    Stanford, United States

    9 h-index

    12 publications

    853 citations

  3. Cornell University

    Ithaca, United States

    7 h-index

    18 publications

    800 citations

  4. European Bioinformatics Institute

    Cambridge, United Kingdom

    6 h-index

    22 publications

    2K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    40 publications

    4.2K citations

  6. National Institutes of Health

    Bethesda, United States

    6 h-index

    45 publications

    5.9K citations

  7. Inserm

    Paris, France

    5 h-index

    20 publications

    538 citations

  8. Vanderbilt University Medical Center

    Nashville, United States

    5 h-index

    16 publications

    596 citations

1–8 of 788

Venues

  1. PLoS ONE

    7 publications · 289 citations

    7

    h-index

  2. Scientific Reports

    7 publications · 254 citations

    7

    h-index

  3. European Journal of Medicinal Chemistry

    6 publications · 194 citations

    6

    h-index

  4. Journal of Biomolecular Structure and Dynamics

    7 publications · 304 citations

    6

    h-index

  5. Drug Discovery Today

    5 publications · 437 citations

    5

    h-index

1–5