Concepedia

Mapk Pathway Mutations

MAPK Pathway Mutations is a molecular pathogenic mechanism characterized by constitutive activation of the mitogen-activated protein kinase signaling cascade due to acquired genetic alterations, primarily in histiocytic neoplasms.

636

Publications

47K

Citations

6.4K

Authors

1.6K

Institutions

Publications per year

2017–2026

328

Parents

Publications

636

Comprehensive molecular characterization of urothelial bladder carcinoma

Zhenlin Ju · Nature · 2014 · 3.1K citations · Full text

, , +17

The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

Eliezer M. Van Allen, Nikhil Wagle, Antje Sucker et al. · Cancer Discovery · 2013 · 940 citations · Full text

, , +17

The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

Hidetoshi Sumimoto, Fumie Imabayashi, Tomoko Iwata et al. · The Journal of Experimental Medicine · 2006 · 713 citations · Full text

, , +17

Germline Mutations in Genes Within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome

Pablo Rodriguez‐Viciana, Osamu Tetsu, William E. Tidyman et al. · Science · 2006 · 570 citations

, , +17

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford et al. · Pigment Cell Research · 2006 · 567 citations

, , +17

1–5 of 636

Authors

6.4K

  1. KA
    Katherine A. Rauen

    University of California, San Francisco, United States

    19 publications · 1.7K citations

    16

    h-index

  2. MT
    Marco Tartaglia

    Bambino Gesù Children's Hospital, Italy

    10 publications · 949 citations

    10

    h-index

  3. MZ
    Martin Zenker

    University Hospital Magdeburg, Germany

    10 publications · 770 citations

    10

    h-index

  4. RJ
    Ryan J. Sullivan

    Massachusetts General Hospital, United States

    9 publications · 936 citations

    9

    h-index

  5. KW
    Karen W. Gripp

    Community Health Systems - Dupont Hospital, United States

    9 publications · 625 citations

    9

    h-index

1–5 of 6.4K

Institutions

1.6K

  1. University of California, San Francisco

    San Francisco, United States

    31 h-index

    292 publications

    17.5K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    29 h-index

    284 publications

    50K citations

  3. Harvard University

    Cambridge, United States

    27 h-index

    220 publications

    35.9K citations

  4. Massachusetts General Hospital

    Boston, United States

    26 h-index

    187 publications

    58.5K citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    26 h-index

    239 publications

    67K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    24 h-index

    192 publications

    63.5K citations

  7. Inserm

    Paris, France

    23 h-index

    142 publications

    14.5K citations

  8. Heidelberg University

    Heidelberg, Germany

    22 h-index

    204 publications

    53.8K citations

1–8 of 1.6K

Venues

  1. Clinical Cancer Research

    30 publications · 2.8K citations

    26

    h-index

  2. American Journal of Medical Genetics Part A

    27 publications · 1.3K citations

    19

    h-index

  3. Journal of Clinical Oncology

    26 publications · 1.2K citations

    17

    h-index

  4. PLoS ONE

    17 publications · 1.1K citations

    15

    h-index

  5. International Journal of Cancer

    13 publications · 855 citations

    13

    h-index

1–5