The BRAF–MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

Hidetoshi Sumimoto, Fumie Imabayashi, Tomoko Iwata, +1

The Journal of Experimental Medicine

Stat3 SignalImmunologyImmunoeditingImmunotherapyCancer Biology +17

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

Hidetoshi Sumimoto, Yohko Kage, Hiroyuki Nunoi, +6

Proceedings of the National Academy of Sciences

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference

Hidetoshi Sumimoto, Makoto Miyagishi, Hiroyuki Miyoshi, +4

Oncogene

Skin CancerMelanomaImmunologyViral OncologyCell Biology +7

HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.

Hiroyuki Kato, Hidetoshi Sumimoto, Philippe Pognonec, +3

Genes & Development

Viral ReplicationImmunologyMolecular BiologyProcessivity FactorHiv-1 Tat +20

Immune Suppression and Resistance Mediated by Constitutive Activation of Wnt/β-Catenin Signaling in Human Melanoma Cells

Tomonori Yaguchi, Yasufumi Goto, Kenji Kido, +7

The Journal of Immunology

Il-10 ExpressionImmunologyImmune RegulationImmunoeditingImmunologic Mechanism +22

RAS–Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers

Hidetoshi Sumimoto, Atsushi Takano, Koji Teramoto, +1

PLoS ONE

Cell DeathPd-l1 GeneCancer BiologyTumor BiologyTumor Immunity +19

Optimization of an siRNA‐expression system with an improved hairpin and its significant suppressive effects in mammalian cells

Makoto Miyagishi, Hidetoshi Sumimoto, Hiroyuki Miyoshi, +2

The Journal of Gene Medicine

Cloning and expression of a cDNA for human cytochrome P-450aldo as related to primary aldosteronism

Takeshi Kawamoto, Yasuhiro Mitsuuchi, Taira Ohnishi, +11

Biochemical and Biophysical Research Communications

Adrenal GlandMolecular PhysiologyAldo-keto ReductaseBiochemistryMedicine +8

Structural and functional characterization of human aromatase <i>P</i>‐450 gene

Katsumi Toda, Masako Terashima, Takeshi Kawamoto, +9

European Journal of Biochemistry

Hepatic AdipoR2 signaling plays a protective role against progression of nonalcoholic steatohepatitis in mice†

Kengo Tomita, Yuichi Oike, Toshiaki Teratani, +14

Hepatology