Makoto Miyagishi

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

Mitsutoshi Yoneyama, Mika Kikuchi, Takashi Natsukawa et al. · Nature Immunology · 2004 · 3.8K citations

Essential Function, Viral Replication, Molecular Virology +10

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

Toshimasa Yamauchi, Junji Kamon, Yusuke Ito et al. · Nature · 2003 · 3.1K citations

Obesity, Metabolic Syndrome, Biochemistry +7

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Akinori Takaoka, Zhichao Wang, Myoung Kwon Choi et al. · Nature · 2007 · 1.7K citations

Molecular Immunology, Innate Immune System, Immunology +5

Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity

Mitsutoshi Yoneyama, Mika Kikuchi, Kanae Matsumoto et al. · The Journal of Immunology · 2005 · 1.6K citations · Full text

U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells

Makoto Miyagishi, Kazunari Taira · Nature Biotechnology · 2002 · 714 citations

Transcriptional Regulation, Medicine, Natural Sciences +8