Concepedia

Lysosomal Compartmentalization

Lysosomal Compartmentalization is a biological mechanism of subcellular organization that segregates degradative enzymes and acidic hydrolases within membrane-bound lysosomes to prevent non-specific degradation of cellular components and to maintain metabolic homeostasis.

908

Publications

58.2K

Citations

3.5K

Authors

956

Institutions

Publications per year

2017–2026

141

Parents

Publications

908

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu et al. · Cell · 2010 · 2.4K citations · Full text

, , +17

CYTOPLASMIC COMPONENTS IN HEPATIC CELL LYSOSOMES

Thomas P. Ashford, Keith R. Porter · The Journal of Cell Biology · 1962 · 829 citations · Full text

, , +10

Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking.

Mitsunori Fukuda · Journal of Biological Chemistry · 1991 · 562 citations · Full text

, , +14

Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival.

John A. Armstrong, P. D’Arcy Hart · The Journal of Experimental Medicine · 1975 · 541 citations · Full text

, , +17

Translocation and clustering of endosomes and lysosomes depends on microtubules.

Rafaele Matteoni, T E Kreis · The Journal of Cell Biology · 1987 · 499 citations · Full text

, , +17

1–5 of 908

Authors

3.5K

  1. UT
    Ulf T. Brunk

    Linköping University, Sweden

    12 publications · 1.3K citations

    11

    h-index

  2. AL
    Al L. Tappel

    University of California, Davis, United States

    9 publications · 811 citations

    9

    h-index

  3. MN
    Michael N. Moore

    Plymouth Marine Laboratory, United Kingdom

    9 publications · 678 citations

    9

    h-index

  4. PM
    Paul M. Tulkens

    UCLouvain, Belgium

    8 publications · 442 citations

    8

    h-index

  5. HG
    Hans Glaumann

    Karolinska Institutet, Sweden

    8 publications · 210 citations

    8

    h-index

1–5 of 3.5K

Institutions

956

  1. National Institutes of Health

    Bethesda, United States

    15 h-index

    43 publications

    5.6K citations

  2. Johns Hopkins University

    Baltimore, United States

    14 h-index

    43 publications

    3.4K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    13 h-index

    30 publications

    1K citations

  4. UCLouvain

    Louvain-la-Neuve, Belgium

    13 h-index

    41 publications

    2.6K citations

  5. Inserm

    Paris, France

    12 h-index

    46 publications

    1.8K citations

  6. Linköping University

    Linköping, Sweden

    12 h-index

    35 publications

    3.7K citations

  7. Harvard University

    Cambridge, United States

    12 h-index

    29 publications

    2.2K citations

  8. Plymouth Marine Laboratory

    Plymouth, United Kingdom

    11 h-index

    38 publications

    2.5K citations

1–8 of 956

Venues

  1. Journal of Biological Chemistry

    JBC · 48 publications · 5.8K citations

    38

    h-index

  2. The Journal of Cell Biology

    JCB · 40 publications · 5.2K citations

    31

    h-index

  3. PubMed

    Repository · 63 publications · 2.3K citations

    25

    h-index

  4. Biochemical and Biophysical Research Communications

    BBRC · 23 publications · 700 citations

    18

    h-index

  5. Experimental Cell Research

    ECR · 19 publications · 671 citations

    16

    h-index

1–5