Concepedia

Lineage-dependent Cell Specification

Lineage-Dependent Cell Specification is a developmental mechanism in which cell fate is determined intrinsically through the inheritance of cytoplasmic determinants during cell division, distinguishing it from extrinsic, signal-mediated specification mechanisms.

46

Publications

2.9K

Citations

257

Authors

110

Institutions

Publications per year

2017–2026

8

Variants

Lineage-dependent Specification

Parents

Publications

46

Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages

Yusuke Ohnishi, Wolfgang Huber, Akiko Tsumura et al. · Nature Cell Biology · 2013 · 318 citations · Full text

, , +16

LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

Da Hye Lee, Jae Oh Park, Tae‐Shin Kim et al. · Nature Communications · 2016 · 201 citations · Full text

, , +16

E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment

Tomokatsu Ikawa, Hiroshi Kawamoto, Ananda W. Goldrath et al. · The Journal of Experimental Medicine · 2006 · 193 citations · Full text

, , +17

Lineage-dependent spatial and functional organization of the mammalian enteric nervous system

Reena Lasrado, Werend Boesmans, Jens Kleinjung et al. · Science · 2017 · 170 citations

, , +17

TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells

Ageliki Tsagaratou, Edahí González‐Avalos, Sini Rautio et al. · Nature Immunology · 2016 · 147 citations

, , +14

1–5 of 46

Authors

257

  1. HH
    Howard Holtzer

    University of Pennsylvania, United States

    2 publications · 52 citations

    2

    h-index

  2. DC
    Daniela Calvigioni

    Karolinska Institutet, Sweden

    1 publications · 75 citations

    1

    h-index

  3. CA
    Chinatsu Arima

    Nagoya University, Japan

    1 publications · 138 citations

    1

    h-index

  4. BL
    Barbara L. Kee

    University of Chicago, United States

    1 publications · 63 citations

    1

    h-index

  5. MP
    Mu-ming Poot

    NYU Langone Health, United States

    1 publications · 17 citations

    1

    h-index

1–5 of 257

Institutions

110

  1. Inserm

    Paris, France

    3 h-index

    15 publications

    911 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    8 publications

    548 citations

  3. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    2 h-index

    2 publications

    126 citations

  4. Columbia University Irving Medical Center

    New York, United States

    2 h-index

    3 publications

    143 citations

  5. University of Chicago

    Chicago, United States

    2 h-index

    4 publications

    246 citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    19 publications

    1K citations

  7. California Institute of Technology

    Pasadena, United States

    2 h-index

    4 publications

    291 citations

  8. Molecular Oncology (United States)

    Gaithersburg, United States

    2 h-index

    12 publications

    1.6K citations

1–8 of 110

Venues

  1. Development

    4 publications · 329 citations

    4

    h-index

  2. Nature Immunology

    3 publications · 280 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 71 citations

    2

    h-index

  4. PubMed

    Repository · 2 publications · 71 citations

    2

    h-index

  5. Neuron

    2 publications · 92 citations

    2

    h-index

1–5