Concepedia

Lineage Differentiation

Lineage Differentiation is a biological framework that specifies the hierarchical developmental pathways through which undifferentiated progenitor cells commit to distinct cellular fates within a tumor, distinguishing itself from general differentiation by emphasizing the phylogenetic-like progression and clonal evolution of cell lineages in neoplastic tissues.

1.8K

Publications

142.1K

Citations

11.5K

Authors

2.3K

Institutions

Publications per year

2017–2026

543

Parents

Publications

1.8K

MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells

Jennifer A. Chan, Anna M. Krichevsky, Kenneth S. Kosik · Cancer Research · 2005 · 2.5K citations

, , +17

Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell

Masatake Osawa, Ken‐ichi Hanada, Hirofumi Hamada et al. · Science · 1996 · 2.1K citations

, , +17

Stem Cell Properties of Human Dental Pulp Stem Cells

Stan Gronthos, Jaime S. Brahim, W. Li et al. · Journal of Dental Research · 2002 · 2.1K citations

, , +17

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

Xuexian O. Yang, Bhanu P. Pappu, Roza Nurieva et al. · Immunity · 2008 · 1.6K citations · Full text

, , +13

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

Lei Zhang, Xin Yu, Liangtao Zheng et al. · Nature · 2018 · 1.5K citations

, , +16

1–5 of 1.8K

Authors

11.5K

  1. TT
    Tom Taghon

    Ghent University Hospital, Belgium

    8 publications · 514 citations

    8

    h-index

  2. SG
    Stan Gronthos

    The University of Adelaide, Australia

    8 publications · 2.8K citations

    8

    h-index

  3. IL
    Irving L. Weissman

    Stanford University, United States

    7 publications · 571 citations

    7

    h-index

  4. SH
    Stuart H. Orkin

    Dana-Farber Cancer Institute, United States

    7 publications · 589 citations

    7

    h-index

  5. HO
    Hongwei Ouyang

    Zhejiang University, China

    6 publications · 563 citations

    6

    h-index

1–5 of 11.5K

Institutions

2.3K

  1. Harvard University

    Cambridge, United States

    46 h-index

    277 publications

    43.3K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    35 h-index

    130 publications

    24.5K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    28 h-index

    132 publications

    22.3K citations

  4. National Institutes of Health

    Bethesda, United States

    27 h-index

    145 publications

    19.4K citations

  5. National Cancer Institute

    Bethesda, United States

    24 h-index

    116 publications

    15.2K citations

  6. Chinese Academy of Sciences

    Beijing, China

    24 h-index

    197 publications

    10.9K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    130 publications

    10.9K citations

  8. Stanford University

    Stanford, United States

    23 h-index

    132 publications

    12.9K citations

1–8 of 2.3K

Venues

  1. PLoS ONE

    76 publications · 4.5K citations

    39

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 45 publications · 9.2K citations

    38

    h-index

  3. Stem Cells

    56 publications · 4.6K citations

    35

    h-index

  4. Nature Communications

    47 publications · 4.9K citations

    35

    h-index

  5. PubMed

    Repository · 63 publications · 3.8K citations

    33

    h-index

1–5