Ligase Structure Function Relationships is a biochemical framework that elucidates how the three-dimensional architecture of DNA ligase enzymes mechanistically determines their catalytic activity, substrate specificity, and molecular interactions in nucleic acid metabolism.
50
Publications
4.3K
Citations
300
Authors
97
Institutions
Publications per year
2017–2026
13
Parents
Publications
50
Global Identification of Modular Cullin-RING Ligase Substrates
Michael J. Emanuele, Andrew E. H. Elia, Qikai Xu et al. · Cell · 2011 · 405 citations · Full text
1–5 of 50
Authors
300
- SS
9
h-index
- BABrenda A. Schulman
St. Jude Children's Research Hospital, United States
3 publications · 970 citations
3
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- DM
3
h-index
- LW
3
h-index
- CD
2
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1–5 of 300
Institutions
97
Kettering University
Flint, United States
10 h-index
28 publications
1.4K citations
Howard Hughes Medical Institute
Chevy Chase, United States
5 h-index
19 publications
6.2K citations
University of Dundee
Dundee, United Kingdom
4 h-index
21 publications
1.8K citations
Harvard University
Cambridge, United States
3 h-index
12 publications
3.7K citations
St. Jude Children's Research Hospital
Memphis, United States
3 h-index
14 publications
4.7K citations
Brigham and Women's Hospital
Boston, United States
3 h-index
13 publications
3.8K citations
Memorial Sloan Kettering Cancer Center
New York, United States
2 h-index
9 publications
431 citations
University of New Mexico
Albuquerque, United States
2 h-index
6 publications
145 citations
1–8 of 97
Venues
- Journal of Biological Chemistry
JBC · 6 publications · 165 citations
6
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- Molecular Cell
4 publications · 807 citations
4
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- Nucleic Acids Research
4 publications · 114 citations
4
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- Nature Chemical Biology
3 publications · 451 citations
3
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- Journal of Molecular Biology
JMB · 3 publications · 125 citations
3
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