The genome of the social amoeba Dictyostelium discoideum

Ludwig Eichinger, Justin A. Pachebat, Gernot Glöckner, +94

Nature

BiologyUnicellular OrganismProtistMolecular EcologyGenetics +5

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

Chanhee Kang, Qikai Xu, Timothy D. Martin, +7

Science

MitophagyAgingImmunologyCell DeathTumor Biology +16

Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma

Giacomo Oliveira, Kari Stromhaug, Susan Klaeger, +23

Nature

Cancer ImmunosurveillanceMelanomaImmunologyAutoimmunityImmunotherapy +3

Global Protein Stability Profiling in Mammalian Cells

Hsueh-Chi S. Yen, Qikai Xu, Danny M. Chou, +2

Science

Protein TurnoverMolecular BiologyGene Expression ProfilingProteomic TechnologyGlobal Transcript Abundance +15

Comprehensive serological profiling of human populations using a synthetic human virome

George Xu, Tomasz Kula, Qikai Xu, +11

Science

Genetic TestingMolecular EpidemiologyViral DiagnosticsGenetic EpidemiologyImmunology +20

A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

Jessica D. Kessler, Kristopher T. Kahle, Tingting Sun, +23

Science

Transcriptional RegulationSystems BiologyCell RegulationOncogenic AgentMedicine +12

Global Identification of Modular Cullin-RING Ligase Substrates

Michael J. Emanuele, Andrew E. H. Elia, Qikai Xu, +9

Cell

Protein AssemblyStructural BioinformaticsProtein FoldingGlobal IdentificationNatural Sciences +4

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

Guang Hu, Jonghwan Kim, Qikai Xu, +3

Genes & Development

Genome-wide Sirna ScreenTranscriptional RegulationSystems BiologyDevelopmental BiologyLineage Plasticity +13

Cancer Proliferation Gene Discovery Through Functional Genomics

Michael R. Schlabach, Ji Luo, Nicole L. Solimini, +14

Science

Systems BiologyFunctional GenomicsSingle Cell SequencingParallel Multiplex MethodologyCancer Genomics +10

Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein

Andrew Ferretti, Tomasz Kula, Yifan Wang, +16

Immunity

Spike ProteinAdaptive Immune SystemLargely ResideImmunologyAntigen Processing +4