Concepedia

Life Span Extension

Life Span Extension is a biological phenomenon characterized by the prolongation of an organism's total lifespan, distinguished within the context of Radiation Hormesis as a dose-dependent effect resulting from adaptive responses to low-level ionizing radiation exposure.

2.2K

Publications

183.9K

Citations

9.2K

Authors

2.1K

Institutions

Publications per year

2017–2026

339

Parents

Publications

2.2K

Aging, Natural Death, and the Compression of Morbidity

James F. Fries · New England Journal of Medicine · 1980 · 3.3K citations

, , +11

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

Ricki J. Colman, Rozalyn M. Anderson, Sterling C. Johnson et al. · Science · 2009 · 2.3K citations · Full text

, , +17

The Biologic Clock: The Mitochondria?

Denham Harman · Journal of the American Geriatrics Society · 1972 · 2K citations

, , +17

Requirement of NAD and <i>SIR2</i> for Life-Span Extension by Calorie Restriction in <i>Saccharomyces cerevisiae</i>

Su-Ju Lin, Pierre‐Antoine Defossez, Leonard Guarente · Science · 2000 · 1.8K citations

, , +17

A Mutant <i>Drosophila</i> Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function

Marc Tatar, A. H. Kopelman, Diane Epstein et al. · Science · 2001 · 1.6K citations

, , +17

1–5 of 2.2K

Authors

9.2K

  1. RS
    Rajindar S. Sohal

    Southern Methodist University, United States

    20 publications · 1.7K citations

    19

    h-index

  2. MK
    Matt Kaeberlein

    University of Washington, United States

    20 publications · 3.9K citations

    18

    h-index

  3. AB
    Andrzej Bartke

    Southern Illinois University School of Medicine, United States

    16 publications · 1.5K citations

    14

    h-index

  4. TE
    Thomas E. Johnson

    University of Colorado Boulder, United States

    14 publications · 1.7K citations

    14

    h-index

  5. SL
    Stephen L. Helfand

    Brown University, United States

    14 publications · 3.1K citations

    13

    h-index

1–5 of 9.2K

Institutions

2.1K

  1. Harvard University

    Cambridge, United States

    35 h-index

    141 publications

    37.9K citations

  2. University of Washington

    Seattle, United States

    33 h-index

    150 publications

    28.6K citations

  3. University of Michigan

    Ann Arbor, United States

    30 h-index

    120 publications

    10.9K citations

  4. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    29 h-index

    145 publications

    18K citations

  5. University of Southern California

    Los Angeles, United States

    29 h-index

    117 publications

    19.5K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    23 h-index

    71 publications

    21.2K citations

  7. University of California, Davis

    Davis, United States

    22 h-index

    59 publications

    4.9K citations

  8. National Institute on Aging

    Baltimore, United States

    20 h-index

    70 publications

    15.6K citations

1–8 of 2.1K

Venues

  1. The Journals of Gerontology Series A

    121 publications · 10.6K citations

    57

    h-index

  2. PubMed

    Repository · 169 publications · 8.2K citations

    49

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 48 publications · 9.1K citations

    40

    h-index

  4. Science

    45 publications · 20.2K citations

    39

    h-index

  5. Journal of Biological Chemistry

    JBC · 28 publications · 3.7K citations

    26

    h-index

1–5