Concepedia

Library Normalization

Library Normalization is a molecular biology technique used in cDNA and gene library construction that reduces the relative abundance of highly expressed or repetitive sequences to achieve a more uniform representation of transcripts or genes within the library, thereby enhancing the discovery of rare and low-abundance sequences.

60

Publications

8.2K

Citations

329

Authors

133

Institutions

Publications per year

2017–2026

7

Parents

Publications

60

Normalization of cDNA microarray data

Gordon K. Smyth · Methods · 2003 · 1.9K citations

, , +11

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

Marie‐Agnès Dillies, Andréa Rau, Julie Aubert et al. · Briefings in Bioinformatics · 2012 · 1.4K citations · Full text

, , +14

Normalization and subtraction: two approaches to facilitate gene discovery.

Maria F. Bonaldo, Greg Lennon, Marcelo B. Soares · Genome Research · 1996 · 526 citations · Full text

, , +14

Construction and characterization of a normalized cDNA library.

Marcelo B. Soares, Maria F. Bonaldo, P Jelene et al. · Proceedings of the National Academy of Sciences · 1994 · 417 citations

, , +15

Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

Ross C. Hardison, John C. Oeltjen, Webb Miller · Genome Research · 1997 · 323 citations · Full text

, , +16

1–5 of 60

Authors

329

  1. YH
    Yoshihide Hayashizaki

    RIKEN Center for Integrative Medical Sciences, Japan

    4 publications · 540 citations

    4

    h-index

  2. PC
    Piero Carninci

    RIKEN Center for Integrative Medical Sciences, Japan

    4 publications · 540 citations

    4

    h-index

  3. DA
    Dmitry A. Shagin

    Institute of Bioorganic Chemistry, Russia

    4 publications · 144 citations

    4

    h-index

  4. MB
    Marcelo B. Soares

    University of Iowa, United States

    4 publications · 982 citations

    4

    h-index

  5. SL
    Sergey Lukyanov

    Institute of Bioorganic Chemistry, Russia

    3 publications · 102 citations

    3

    h-index

1–5 of 329

Institutions

133

  1. RIKEN Center for Integrative Medical Sciences

    Yokohama, Japan

    4 h-index

    25 publications

    3.1K citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    11 publications

    833 citations

  3. Institute of Bioorganic Chemistry

    Moscow, Russia

    4 h-index

    15 publications

    535 citations

  4. The University of Queensland

    Brisbane, Australia

    4 h-index

    16 publications

    1.2K citations

  5. Japan Science and Technology Agency

    Tokyo, Japan

    3 h-index

    6 publications

    148 citations

  6. The University of Tokyo

    Tokyo, Japan

    3 h-index

    21 publications

    3.4K citations

  7. Center for Genomic Science

    Milan, Italy

    3 h-index

    9 publications

    515 citations

  8. Lawrence Berkeley National Laboratory

    Berkeley, United States

    2 h-index

    19 publications

    3.2K citations

1–8 of 133

Venues

  1. Genome Research

    GR · 7 publications · 1.5K citations

    7

    h-index

  2. Methods in molecular biology

    Book series · 4 publications · 71 citations

    4

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 849 citations

    3

    h-index

  4. BioTechniques

    3 publications · 52 citations

    3

    h-index

  5. Analytical Biochemistry

    2 publications · 62 citations

    2

    h-index

1–5