Concepedia

Irreversible Differentiation

Irreversible Differentiation is a biological process in which a progenitor cell undergoes terminal differentiation into a specialized cell type, characterized by the permanent loss of proliferative capacity and the inability to revert to a less differentiated state.

38

Publications

3.2K

Citations

139

Authors

66

Institutions

Publications per year

2017–2026

5

Parents

Publications

38

Naive T Cells Transiently Acquire a Memory-like Phenotype during Homeostasis-Driven Proliferation

Ananda W. Goldrath, Lisa Bogatzki, Michael J. Bevan · The Journal of Experimental Medicine · 2000 · 629 citations · Full text

, , +16

Regulation of Telomerase Activity in Immortal Cell Lines

Shawn E. Holt, Woodring E. Wright, Jerry W. Shay · Molecular and Cellular Biology · 1996 · 365 citations · Full text

, , +16

Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells.

J F Boylan, Lorraine J. Gudas · The Journal of Cell Biology · 1991 · 325 citations · Full text

, , +14

Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division.

Robert G. Ramsay, Kazuma Ikeda, Richard A. Rifkind et al. · Proceedings of the National Academy of Sciences · 1986 · 199 citations

, , +14

Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module

Juliana L. Matos, On Sun Lau, Charles Hachez et al. · eLife · 2014 · 133 citations · Full text

, , +17

1–5 of 38

Authors

139

  1. MN
    Miguel Navarro

    Instituto de Parasitología y Biomedicina "López - Neyra", Spain

    2 publications · 108 citations

    2

    h-index

  2. GB
    Gary Borzillo

    Pfizer (United States), United States

    2 publications · 156 citations

    2

    h-index

  3. MS
    Manuel Saldivia

    Instituto de Parasitología y Biomedicina "López - Neyra", Spain

    2 publications · 108 citations

    2

    h-index

  4. MN
    Michael N. Hall

    University of Basel, Switzerland

    2 publications · 108 citations

    2

    h-index

  5. JB
    Jean-Mathieu Bart

    Université de Franche-Comté, France

    2 publications · 108 citations

    2

    h-index

1–5 of 139

Institutions

66

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    7 publications

    2.1K citations

  2. St. Jude Children's Research Hospital

    Memphis, United States

    2 h-index

    6 publications

    468 citations

  3. Instituto de Parasitología y Biomedicina "López - Neyra"

    Armilla, Spain

    2 h-index

    11 publications

    621 citations

  4. University of Basel

    Basel, Switzerland

    2 h-index

    2 publications

    108 citations

  5. Consejo Superior de Investigaciones Científicas

    Madrid, Spain

    2 h-index

    11 publications

    621 citations

  6. Stanford University

    Stanford, United States

    2 h-index

    5 publications

    655 citations

  7. Centro Nacional de Medicina Tropical

    Madrid, Spain

    2 h-index

    2 publications

    108 citations

  8. Indian Institute of Science Bangalore

    Bengaluru, India

    1 h-index

    3 publications

    264 citations

1–8 of 66

Venues

  1. Molecular and Cellular Biology

    MCB · 3 publications · 521 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 344 citations

    3

    h-index

  3. The Journal of Cell Biology

    JCB · 3 publications · 489 citations

    3

    h-index

  4. Journal of Cellular Physiology

    2 publications · 34 citations

    2

    h-index

  5. Biochemical Society Transactions

    1 publications · 27 citations

    1

    h-index

1–5