Manuel Saldivia

The Susceptibility of Trypanosomatid Pathogens to PI3/mTOR Kinase Inhibitors Affords a New Opportunity for Drug Repurposing

Rosario Díaz-González, F Kuhlmann, Cristina Galan-Rodriguez et al. · PLoS neglected tropical diseases · 2011 · 89 citations · Full text

Veterinary Medicine, Infectious Diseases, Pharmacology +17

Third target of rapamycin complex negatively regulates development of quiescence in <i>Trypanosoma brucei</i>

Antonio Barquilla, Manuel Saldivia, Rosario Díaz-González et al. · Proceedings of the National Academy of Sciences · 2012 · 81 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

Manuel Saldivia, Eric Fang, Xiaolei Ma et al. · Nature Microbiology · 2020 · 71 citations

Life Sciences, Cell Biology, Molecular Biology +14

The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei

Manuel Saldivia, Gloria Ceballos-Pérez, Jean-Mathieu Bart et al. · Cell Reports · 2016 · 53 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria‐mediated apoptosis and DNA damage in p53 mutant leukemic T cells

María José Ruiz-Magaña, José Manuel Rodríguez-Vargas, Jorge Carlos Morales et al. · International Journal of Cancer · 2011 · 48 citations · Full text

Medicine, Oncology, Pharmacology +17