Concepedia

Terminal Differentiation

Terminal Differentiation is a biological process in which a precursor or stem cell undergoes irreversible specialization into a fully functional, mature cell type, characterized by the complete cessation of cell division and the stable expression of tissue-specific functions.

955

Publications

87.5K

Citations

4.8K

Authors

1.2K

Institutions

Publications per year

2017–2026

81

Parents

Children

Publications

955

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez et al. · Nature · 2004 · 2.2K citations

, , +14

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

Jason R. Spence, Christopher N. Mayhew, Scott A. Rankin et al. · Nature · 2010 · 1.9K citations · Full text

, , +16

Efficient differentiation of human embryonic stem cells to definitive endoderm

Kevin A. D’Amour, Alan D. Agulnick, Susan Eliazer et al. · Nature Biotechnology · 2005 · 1.7K citations

, , +16

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

Sidney Strickland, Vijak Mahdavi · Cell · 1978 · 1.4K citations

, , +14

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

Sylvie Castaigné, Christine Chomienne, MT Daniel et al. · Blood · 1990 · 1.2K citations · Full text

, , +11

1–5 of 955

Authors

4.8K

  1. AM
    Anna M. Wobus

    Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK), Germany

    8 publications · 596 citations

    8

    h-index

  2. FM
    Fiona M. Watt

    The Honourable Society of Lincoln's Inn, United Kingdom

    7 publications · 1.2K citations

    7

    h-index

  3. HC
    Hans Clevers

    Hubrecht Institute for Developmental Biology and Stem Cell Research, Netherlands

    6 publications · 2.2K citations

    6

    h-index

  4. RG
    Ren‐Shan Ge

    Wenzhou Medical University, China

    6 publications · 177 citations

    6

    h-index

  5. CM
    Catherine M. Verfaillie

    KU Leuven, Belgium

    6 publications · 250 citations

    6

    h-index

1–5 of 4.8K

Institutions

1.2K

  1. Harvard University

    Cambridge, United States

    30 h-index

    142 publications

    35.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    20 h-index

    51 publications

    25.1K citations

  3. Inserm

    Paris, France

    17 h-index

    85 publications

    5.4K citations

  4. University of Pennsylvania

    Philadelphia, United States

    16 h-index

    70 publications

    10.3K citations

  5. National Institutes of Health

    Bethesda, United States

    15 h-index

    50 publications

    4.8K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    15 h-index

    50 publications

    8.7K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    56 publications

    6.7K citations

  8. Stanford University

    Stanford, United States

    14 h-index

    88 publications

    25.4K citations

1–8 of 1.2K

Venues

  1. Blood

    47 publications · 6.5K citations

    37

    h-index

  2. Biochemical and Biophysical Research Communications

    BBRC · 43 publications · 2.8K citations

    29

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 39 publications · 4K citations

    28

    h-index

  4. Developmental Biology

    38 publications · 2.7K citations

    28

    h-index

  5. Experimental Cell Research

    ECR · 45 publications · 3.2K citations

    28

    h-index

1–5