Concepedia

Intratumor Evolution

Intratumor Evolution is a biological process denoting the heterogeneous development of genetically distinct subclones within a single tumor over time, driven by differential accumulation of somatic mutations and selective pressures in the tumor microenvironment.

125

Publications

23K

Citations

1.4K

Authors

448

Institutions

Publications per year

2017–2026

60

Parents

Publications

125

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger, Andrew J. Rowan, Stuart Horswell et al. · New England Journal of Medicine · 2012 · 7.8K citations · Full text

, , +14

Tracking the Evolution of Non–Small-Cell Lung Cancer

Mariam Jamal‐Hanjani, Gareth A. Wilson, Nicholas McGranahan et al. · New England Journal of Medicine · 2017 · 2.4K citations · Full text

, , +17

Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics

Andrea Sottoriva, Inmaculada Spiteri, Sara Piccirillo et al. · Proceedings of the National Academy of Sciences · 2013 · 1.8K citations · Full text

, , +17

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Elza C. de Bruin, Nicholas McGranahan, Richard Mitter et al. · Science · 2014 · 1.2K citations · Full text

, , +17

Patient-derived xenografts undergo mouse-specific tumor evolution

Uri Ben‐David, Gavin Ha, Yuen‐Yi Tseng et al. · Nature Genetics · 2017 · 716 citations · Full text

, , +4

1–5 of 125

Authors

1.4K

  1. CS
    Charles Swanton

    University College London, United Kingdom

    13 publications · 12.7K citations

    13

    h-index

  2. NM
    Nicholas McGranahan

    University College London, United Kingdom

    10 publications · 4.3K citations

    10

    h-index

  3. PA
    P. Andrew Futreal

    The University of Texas MD Anderson Cancer Center, United States

    7 publications · 8.9K citations

    7

    h-index

  4. FM
    Franziska Michor

    Dana-Farber Cancer Institute, United States

    5 publications · 1.2K citations

    5

    h-index

  5. NJ
    Nicolai J. Birkbak

    University College London, United Kingdom

    5 publications · 2.9K citations

    5

    h-index

1–5 of 1.4K

Institutions

448

  1. University College London

    London, United Kingdom

    14 h-index

    280 publications

    455.8K citations

  2. CRUK Lung Cancer Centre of Excellence

    Manchester, United Kingdom

    13 h-index

    177 publications

    212.2K citations

  3. Cancer Research UK

    London, United Kingdom

    12 h-index

    156 publications

    215.8K citations

  4. Harvard University

    Cambridge, United States

    11 h-index

    22 publications

    13.8K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    10 h-index

    141 publications

    19.4K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    7 h-index

    19 publications

    7.4K citations

  7. London Cancer

    London, United Kingdom

    7 h-index

    104 publications

    29.8K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    6 h-index

    15 publications

    3.1K citations

1–8 of 448

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 2.6K citations

    7

    h-index

  2. Nature Communications

    5 publications · 663 citations

    5

    h-index

  3. Oncotarget

    5 publications · 555 citations

    5

    h-index

  4. Nature Genetics

    4 publications · 1.2K citations

    5

    h-index

  5. Cancer Research

    5 publications · 284 citations

    5

    h-index

1–5