Elza C. de Bruin

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Elza C. de Bruin, Nicholas McGranahan, Richard Mitter et al. · Science · 2014 · 1.2K citations · Full text

Medicine, Genetics, Oncology +17

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

Nicholas McGranahan, Francesco Favero, Elza C. de Bruin et al. · Science Translational Medicine · 2015 · 712 citations · Full text

Medicine, Genetics, Oncology +16

Capivasertib in Hormone Receptor–Positive Advanced Breast Cancer

Nicholas C. Turner, Mafalda Oliveira, Sacha J. Howell et al. · New England Journal of Medicine · 2023 · 704 citations · Full text

Medicine, Oncology, Pharmacology +16

Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial

Peter Schmid, Jacinta Abraham, Stephen Chan et al. · Journal of Clinical Oncology · 2019 · 389 citations · Full text

Medicine, Oncology, Pharmacology +16

Reduced <i>NF1</i> Expression Confers Resistance to EGFR Inhibition in Lung Cancer

Elza C. de Bruin, Catherine Cowell, Patricia H. Warne et al. · Cancer Discovery · 2014 · 209 citations · Full text

Medicine, Oncology, Pharmacology +17