Elza C. de Bruin

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

Elza C. de Bruin, Nicholas McGranahan, Richard Mitter et al. · Science · 2014 · 1.1K citations · Full text

Engineering, Genetics, Former Smokers +18

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

Nicholas McGranahan, Francesco Favero, Elza C. de Bruin et al. · Science Translational Medicine · 2015 · 689 citations · Full text

Capivasertib Plus Paclitaxel Versus Placebo Plus Paclitaxel As First-Line Therapy for Metastatic Triple-Negative Breast Cancer: The PAKT Trial

Peter Schmid, Jacinta Abraham, Stephen Chan et al. · Journal of Clinical Oncology · 2019 · 373 citations · Full text

Reduced <i>NF1</i> Expression Confers Resistance to EGFR Inhibition in Lung Cancer

Elza C. de Bruin, Catherine Cowell, Patricia H. Warne et al. · Cancer Discovery · 2014 · 205 citations · Full text

Lung Inflammation, Pathology, Cancer Biology +16

A Phase I Open-Label Study to Identify a Dosing Regimen of the Pan-AKT Inhibitor AZD5363 for Evaluation in Solid Tumors and in <i>PIK3CA</i> -Mutated Breast and Gynecologic Cancers

Udai Banerji, Emma Dean, José Alejandro Pérez Fidalgo et al. · Clinical Cancer Research · 2017 · 139 citations · Full text