Sacha J. Howell

Capivasertib in Hormone Receptor–Positive Advanced Breast Cancer

Nicholas C. Turner, Mafalda Oliveira, Sacha J. Howell et al. · New England Journal of Medicine · 2023 · 704 citations · Full text

Medicine, Oncology, Pharmacology +16

Regulation of Breast Cancer Stem Cell Activity by Signaling through the Notch4 Receptor

Hannah Harrison, Gillian Farnie, Sacha J. Howell et al. · Cancer Research · 2010 · 530 citations · Full text

Medicine, Cell Biology, Oncology +17

Fulvestrant plus capivasertib versus placebo after relapse or progression on an aromatase inhibitor in metastatic, oestrogen receptor-positive breast cancer (FAKTION): a multicentre, randomised, controlled, phase 2 trial

Robert H. Jones, Angela Casbard, Margherita Carucci et al. · The Lancet Oncology · 2020 · 227 citations · Full text

Medicine, Oncology, Pharmacology +17

Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms

Jagdeep Singh, Gillian Farnie, Nigel Bundred et al. · Clinical Cancer Research · 2012 · 212 citations · Full text

Medicine, Cell Biology, Oncology +17

Detection of PIK3CA mutations in circulating free DNA in patients with breast cancer

Andrew Wardley, J. Michael Dixon, Anne Armstrong et al. · Breast Cancer Research and Treatment · 2010 · 199 citations · Full text

Medicine, Genetics, Oncology +16