Concepedia

Interaction Interface Mapping

Interaction Interface Mapping is a computational or experimental method that identifies and characterizes the specific regions on protein surfaces involved in binding interactions with other proteins, thereby distinguishing itself from broader interaction detection techniques by focusing on the precise spatial and physicochemical determinants of molecular contact.

60

Publications

4.4K

Citations

393

Authors

127

Institutions

Publications per year

2017–2026

15

Parents

Publications

60

The protein–protein interaction map of Helicobacter pylori

Jean‐Christophe Rain, Luc Selig, Hilde De Reuse et al. · Nature · 2001 · 1.1K citations

, , +13

COCOMAPS: a web application to analyze and visualize contacts at the interface of biomolecular complexes

Anna Vangone, Raffaele Spinelli, Vittorio Scarano et al. · Bioinformatics · 2011 · 277 citations · Full text

, , +17

Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition

Patrick J. Lupardus, Mark Ultsch, Heidi J.A. Wallweber et al. · Proceedings of the National Academy of Sciences · 2014 · 220 citations · Full text

, , +17

Protein interactions in human genetic diseases

Benjamin Schuster‐Böckler, Alex Bateman · Genome biology · 2008 · 123 citations · Full text

, , +14

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo

Claire Dobson, Paul W. A. Devine, Jonathan J. Phillips et al. · Scientific Reports · 2016 · 123 citations · Full text

, , +17

1–5 of 60

Authors

393

  1. SH
    Samuel H. Wilson

    National Institutes of Health, United States

    2 publications · 82 citations

    2

    h-index

  2. GW
    Gerhard Wagner

    Harvard University, United States

    2 publications · 150 citations

    2

    h-index

  3. GP
    Gregory P. Mullen

    UConn Health, United States

    2 publications · 82 citations

    2

    h-index

  4. SE
    Sheena E. Radford

    University of Leeds, United Kingdom

    2 publications · 180 citations

    2

    h-index

  5. AM
    Assen Marintchev

    Harvard University, United States

    2 publications · 136 citations

    2

    h-index

1–5 of 393

Institutions

127

  1. Harvard University

    Cambridge, United States

    4 h-index

    21 publications

    1.4K citations

  2. University of Toronto

    Toronto, Canada

    3 h-index

    23 publications

    945 citations

  3. Medical Research Council

    London, United Kingdom

    3 h-index

    9 publications

    406 citations

  4. The University of Sydney

    Sydney, Australia

    3 h-index

    12 publications

    358 citations

  5. UConn Health

    Farmington, United States

    2 h-index

    9 publications

    365 citations

  6. National Institutes of Health

    Bethesda, United States

    2 h-index

    7 publications

    455 citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    2 publications

    90 citations

  8. Institute of Structural and Molecular Biology

    London, United Kingdom

    2 h-index

    8 publications

    454 citations

1–8 of 127

Venues

  1. Journal of Biological Chemistry

    JBC · 6 publications · 351 citations

    6

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 533 citations

    5

    h-index

  3. Nature Communications

    3 publications · 162 citations

    3

    h-index

  4. Biochemistry

    3 publications · 120 citations

    3

    h-index

  5. Scientific Reports

    3 publications · 220 citations

    3

    h-index

1–5