Concepedia

Humanized Models

Humanized Models is an experimental disease model that incorporates human biological components, such as cells, tissues, or genes, into a non-human system to more accurately recapitulate human physiology and pathophysiology within a controlled experimental context.

289

Publications

20.1K

Citations

2.7K

Authors

785

Institutions

Publications per year

2017–2026

153

Parents

Publications

289

Humanized mice in translational biomedical research

Leonard D. Shultz, Fumihiko Ishikawa, Dale L. Greiner · Nature reviews. Immunology · 2007 · 1.3K citations

, , +7

Humanized mice in translational biomedical research

Ld Shultz · The Mouseion at the JAXlibrary (Jackson Laboratory) · 2007 · 1K citations

, , +7

Development and function of human innate immune cells in a humanized mouse model

Anthony Rongvaux, Tim Willinger, Jan Martínek et al. · Nature Biotechnology · 2014 · 760 citations · Full text

, , +14

A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice

Wolfgang Enard, Sabine Gehre, Kurt Hammerschmidt et al. · Cell · 2009 · 617 citations · Full text

, , +12

A humanized system for pharmacologic control of gene expression

Victor M. Rivera, Tim Clackson, Sridaran Natesan et al. · Nature Medicine · 1996 · 544 citations

, , +9

1–5 of 289

Authors

2.7K

  1. LD
    Leonard D. Shultz

    Jackson Laboratory, United States

    6 publications · 1.6K citations

    6

    h-index

  2. RA
    Ramesh Akkina

    Colorado State University, United States

    6 publications · 268 citations

    6

    h-index

  3. LS
    Lishan Su

    University of North Carolina at Chapel Hill, United States

    5 publications · 426 citations

    5

    h-index

  4. DL
    Dale L. Greiner

    University of Massachusetts Chan Medical School, United States

    4 publications · 1.4K citations

    4

    h-index

  5. JV
    J. Víctor García

    University of North Carolina at Chapel Hill, United States

    4 publications · 245 citations

    4

    h-index

1–5 of 2.7K

Institutions

785

  1. Harvard University

    Cambridge, United States

    16 h-index

    71 publications

    3.6K citations

  2. Inserm

    Paris, France

    15 h-index

    98 publications

    5K citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    11 h-index

    61 publications

    4.4K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    21 publications

    2.1K citations

  5. National Institutes of Health

    Bethesda, United States

    10 h-index

    78 publications

    4.4K citations

  6. Sorbonne Université

    Paris, France

    9 h-index

    33 publications

    1.9K citations

  7. Massachusetts General Hospital

    Boston, United States

    9 h-index

    28 publications

    2.2K citations

  8. Jackson Laboratory

    Bar Harbor, United States

    9 h-index

    25 publications

    4K citations

1–8 of 785

Venues

  1. PLoS ONE

    10 publications · 359 citations

    10

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 758 citations

    9

    h-index

  3. Scientific Reports

    9 publications · 520 citations

    9

    h-index

  4. The Journal of Immunology

    JI · 8 publications · 341 citations

    8

    h-index

  5. JCI Insight

    6 publications · 339 citations

    6

    h-index

1–5