Concepedia

High-throughput Library Selection

High-Throughput Library Selection is a high-throughput experimental method in the field of antibody engineering that enables the rapid screening and isolation of antigen-specific binders from large, diverse libraries of variant proteins through iterative cycles of selection and amplification.

108

Publications

5.4K

Citations

752

Authors

244

Institutions

Publications per year

2017–2026

41

Parents

Publications

108

Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites

M. He · Nucleic Acids Research · 1997 · 267 citations · Full text

, , +17

Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays

Madhumita Chatterjee, Saroj Kant Mohapatra, Alexei Ionan et al. · Cancer Research · 2006 · 203 citations · Full text

, , +17

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

Yingda Xu, William P. Roach, T. Sun et al. · Protein Engineering Design and Selection · 2013 · 181 citations

, , +17

DNA Shuffling of Adeno-associated Virus Yields Functionally Diverse Viral Progeny

James T. Koerber, Jae‐Hyung Jang, David V. Schaffer · Molecular Therapy · 2008 · 179 citations · Full text

, , +16

High-Throughput Selection of Effective RNAi Probes for Gene Silencing

Rajeev Kumar, Douglas S. Conklin, Vivek Mittal · Genome Research · 2003 · 177 citations · Full text

, , +14

1–5 of 108

Authors

752

  1. DV
    David V. Schaffer

    University of California, Berkeley, United States

    4 publications · 266 citations

    4

    h-index

  2. AB
    Andrew Bradbury

    Los Alamos National Laboratory, United States

    3 publications · 110 citations

    3

    h-index

  3. GW
    Gerald Walter

    Max Planck Institute for Molecular Genetics, Germany

    2 publications · 41 citations

    2

    h-index

  4. GS
    Gerald Schwank

    University of Zurich, Switzerland

    2 publications · 98 citations

    2

    h-index

  5. IJ
    Ilya J. Finkelstein

    The University of Texas at Austin, United States

    2 publications · 103 citations

    2

    h-index

1–5 of 752

Institutions

244

  1. Harvard University

    Cambridge, United States

    7 h-index

    33 publications

    2.5K citations

  2. Scripps Research Institute

    San Diego, United States

    6 h-index

    27 publications

    1.1K citations

  3. University of California, Berkeley

    Berkeley, United States

    4 h-index

    21 publications

    1.1K citations

  4. The University of Texas at Austin

    Austin, United States

    4 h-index

    25 publications

    800 citations

  5. University of Zurich

    Zurich, Switzerland

    4 h-index

    23 publications

    1.1K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    11 publications

    731 citations

  7. ETH Zurich

    Zurich, Switzerland

    3 h-index

    13 publications

    1.4K citations

  8. Karolinska Institutet

    Stockholm, Sweden

    3 h-index

    5 publications

    98 citations

1–8 of 244

Venues

  1. Journal of Immunological Methods

    5 publications · 227 citations

    5

    h-index

  2. Journal of the American Chemical Society

    JACS · 4 publications · 176 citations

    4

    h-index

  3. Nucleic Acids Research

    4 publications · 532 citations

    4

    h-index

  4. Analytical Biochemistry

    3 publications · 54 citations

    3

    h-index

  5. Protein Engineering Design and Selection

    PEDS · 3 publications · 247 citations

    3

    h-index

1–5