Substrate and Functional Diversity of Lysine Acetylation Revealed by a Proteomics Survey

Sung Chan Kim, Robert W. Sprung, Yue Chen, +11

Molecular Cell

Protein ChemistryBiochemistryFunctional DiversityProtein FoldingNatural Sciences +7

Biophysical properties of the clinical-stage antibody landscape

Tushar Jain, Tingwan Sun, Stéphanie Durand, +16

Proceedings of the National Academy of Sciences

Immunocytochemical TechniqueEngineeringImmunologyImmunotherapyMultiple Biophysical Metrics +16

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

Yingda Xu, William P. Roach, T. Sun, +9

Protein Engineering Design and Selection

Deamidation and isomerization liability analysis of 131 clinical-stage antibodies

Xiaojun Lu, R. Paul Nobrega, Heather Lynaugh, +6

mAbs

Peptide EngineeringRelevant EpitopeImmunotherapyBioanalysisChemical Stability +14

Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS

Jaeick Lee, Yingda Xu, Yue Chen, +4

Molecular & Cellular Proteomics

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

Yuqi Liu, Isabelle Caffry, Jiemin Wu, +10

mAbs

NanoparticlesImmunocytochemical TechniqueEngineeringHigh ThroughputProtein Nanoparticles +15

14‐3‐3γ binds to MDMX that is phosphorylated by UV‐activated Chk1, resulting in p53 activation

Yetao Jin, Mu‐Shui Dai, Steven Lu, +4

The EMBO Journal

A Clean, More Efficient Method for In-Solution Digestion of Protein Mixtures without Detergent or Urea

Sung Chan Kim, Yue Chen, Shama P. Mirza, +4

Journal of Proteome Research

Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability

Laila Shehata, Daniel P. Maurer, Anna Z. Wec, +9

Cell Reports

Non‐specific, on‐probe cleanup methods for MALDI‐MS samples

Yingda Xu, Merlin L. Bruening, J. Throck Watson

Mass Spectrometry Reviews

EngineeringSmart PolymerSample TreatmentEffect Analyte AdsorptionAnalytical Instrumentation +15