Heather Lynaugh

Biophysical properties of the clinical-stage antibody landscape

Tushar Jain, Tingwan Sun, Stéphanie Durand et al. · Proceedings of the National Academy of Sciences · 2017 · 600 citations · Full text

Immunocytochemical Technique, Engineering, Immunology +18

Production of monoclonal antibodies by glycoengineered Pichia pastoris

Thomas I. Potgieter, Michael Cukan, J. E. Drummond et al. · Journal of Biotechnology · 2008 · 157 citations

Engineering, Glycobiology, Biotechnology +4

Deamidation and isomerization liability analysis of 131 clinical-stage antibodies

Xiaojun Lu, R. Paul Nobrega, Heather Lynaugh et al. · mAbs · 2018 · 140 citations · Full text

Peptide Engineering, Relevant Epitope, Immunotherapy +16

Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability

Laila Shehata, Daniel P. Maurer, Anna Z. Wec et al. · Cell Reports · 2019 · 98 citations · Full text

High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice

Ryan L. Kelly, Tingwan Sun, Tushar Jain et al. · mAbs · 2015 · 91 citations · Full text

Immunocytochemical Technique, Immunology, Immunodominance +21