Concepedia

Glycan-based Conjugation

Glycan-Based Conjugation is a site-specific antibody conjugation method that exploits the conserved N-glycan structures within the Fc region of immunoglobulins as chemical handles for the attachment of payloads, thereby enabling controlled modification without direct interference with the antigen-binding domains.

182

Publications

8.9K

Citations

991

Authors

267

Institutions

Publications per year

2017–2026

54

Parents

Publications

182

A novel glyco-conjugate vaccine against fungal pathogens

Antonella Torosantucci, Carla Bromuro, Paola Chiani et al. · The Journal of Experimental Medicine · 2005 · 443 citations · Full text

, , +17

‘Multicopy Multivalent’ Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines

Alison L. Parry, Natasha A. Clemson, James L. Ellis et al. · Journal of the American Chemical Society · 2013 · 224 citations · Full text

, , +17

Site-Specific Antibody–Drug Conjugation through Glycoengineering

Qun Zhou, James E. Stefano, Charlene Manning et al. · Bioconjugate Chemistry · 2014 · 218 citations

, , +17

Immunization of breast cancer patients using a synthetic sialyl-Tn glycoconjugate plus Detox adjuvant

Grant D. MacLean, Mark A. Reddish, R. Rao Koganty et al. · Cancer Immunology Immunotherapy · 1993 · 183 citations · Full text

, , +16

Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads

Takashi Nakada, Takeshi Masuda, Hiroyuki Naito et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 169 citations

, , +14

1–5 of 182

Authors

991

  1. RA
    Roberto Adamo

    Toscana Life Sciences, Italy

    8 publications · 501 citations

    8

    h-index

  2. LW
    Lai‐Xi Wang

    University of Maryland, Baltimore, United States

    7 publications · 215 citations

    7

    h-index

  3. CO
    Chong Ou

    University of Maryland, College Park, United States

    7 publications · 215 citations

    7

    h-index

  4. FM
    Francesca Micoli

    Toscana Life Sciences, Italy

    6 publications · 253 citations

    6

    h-index

  5. MA
    Martin Allan

    Toscana Life Sciences, Italy

    5 publications · 341 citations

    5

    h-index

1–5 of 991

Institutions

267

  1. Toscana Life Sciences

    Siena, Italy

    9 h-index

    68 publications

    2.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    31 publications

    915 citations

  3. National Institutes of Health

    Bethesda, United States

    7 h-index

    27 publications

    1.6K citations

  4. University of Maryland, College Park

    College Park, United States

    7 h-index

    39 publications

    1.3K citations

  5. Center for Cancer Research

    Bethesda, United States

    6 h-index

    27 publications

    1.6K citations

  6. Novartis (Italy)

    Milan, Italy

    6 h-index

    60 publications

    4K citations

  7. National Cancer Institute

    Bethesda, United States

    6 h-index

    14 publications

    864 citations

  8. University of Oxford

    Oxford, United Kingdom

    6 h-index

    20 publications

    1.3K citations

1–8 of 267

Venues

  1. Bioconjugate Chemistry

    26 publications · 1.1K citations

    18

    h-index

  2. ACS Chemical Biology

    9 publications · 421 citations

    9

    h-index

  3. Angewandte Chemie International Edition

    7 publications · 638 citations

    7

    h-index

  4. PubMed

    Repository · 7 publications · 337 citations

    7

    h-index

  5. Journal of the American Chemical Society

    JACS · 6 publications · 559 citations

    6

    h-index

1–5