A novel glyco-conjugate vaccine against fungal pathogens

Antonella Torosantucci, Carla Bromuro, Paola Chiani, +9

The Journal of Experimental Medicine

Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence

Antonella Torosantucci, Paola Chiani, Carla Bromuro, +10

PLoS ONE

An Anti-β-Glucan Monoclonal Antibody Inhibits Growth and Capsule Formation of <i>Cryptococcus neoformans</i> In Vitro and Exerts Therapeutic, Anticryptococcal Activity In Vivo

Anna Rachini, Donatella Pietrella, Patrizia Lupo, +7

Infection and Immunity

Antifungal AgentHealth SciencesMicrobial PathogensMab 2G8Immunology +12

Elevated aspartic proteinase secretion and experimental pathogenicity of Candida albicans isolates from oral cavities of subjects infected with human immunodeficiency virus

Flavia De Bernardis, Paola Chiani, Massimo Ciccozzi, +6

Infection and Immunity

Medical MicrobiologyCharacters High ProteinaseOral CavitiesAspartic Proteinase SecretionHuman Retrovirus +12

Beta-glucan-CRM197 conjugates as candidates antifungal vaccines

Carla Bromuro, Maria Rosaria Romano, Paola Chiani, +8

Vaccine

VaccinationImmunologyImmunotherapeuticsBeta-glucan-crm197 ConjugatesVaccine Design +2

Interplay between Protective and Inhibitory Antibodies Dictates the Outcome of Experimentally Disseminated Candidiasis in Recipients of a<i>Candida albicans</i>Vaccine

Carla Bromuro, Antonella Torosantucci, Paola Chiani, +3

Infection and Immunity

Experimentally Disseminated CandidiasisImmunodeficienciesHumoral ResponseImmunologyImmunodominance +18

A β-glucan-conjugate vaccine and anti-β-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique

Donatella Pietrella, Anna Rachini, Antonella Torosantucci, +9

Vaccine

VaccinationMucosal VaccinationVaccine DevelopmentMedicineMurine Vaginal Candidiasis +8

Antiretroviral Therapy with Protease Inhibitors Has an Early, Immune Reconstitution–Independent Beneficial Effect on<i>Candida</i>Virulence and Oral Candidiasis in Human Immunodeficiency Virus–Infected Subjects

Antonio Cassone, Evelina Tacconelli, Flavia De Bernardis, +4

The Journal of Infectious Diseases

Differential chemokine response of human monocytes to yeast and hyphal forms of Candida albicans and its relation to the beta-1,6 glucan of the fungal cell wall.

Antonella Torosantucci, Paola Chiani, Antonio Cassone

PubMed

Chemokine BiologyFungal Cell WallFungal Cell BiologyImmunologyCell Death +18

The interaction of human dendritic cells with yeast and germ-tube forms of <i>Candida albicans</i> leads to efficient fungal processing, dendritic cell maturation, and acquisition of a Th1 response-promoting function

Giulia Romagnoli, Roberto Nisini, Paola Chiani, +4

Journal of Leukocyte Biology