Concepedia

Germline Competence

Germline Competence is the intrinsic developmental potential of a cell to adopt a germ cell fate, distinguished from broader pluripotency by its specific capacity to initiate and sustain the molecular program required for primordial germ cell specification and subsequent transmission of genetic and epigenetic information across generations.

67

Publications

6.5K

Citations

356

Authors

120

Institutions

Publications per year

2017–2026

13

Parents

Publications

67

HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

, , +16

Germline transmission of genetically modified primordial germ cells

Marie‐Cecile van de Lavoir, Jennifer H. Diamond, Philip A. Leighton et al. · Nature · 2006 · 493 citations

, , +14

A Novel ES Cell Line, TT2, with High Germline-Differentiating Potency

Takeshi Yagi, Tomoyuki Tokunaga, Yasuhide Furuta et al. · Analytical Biochemistry · 1993 · 470 citations

, , +11

Principles of early human development and germ cell program from conserved model systems

Toshihiro Kobayashi, Haixin Zhang, Walfred W. C. Tang et al. · Nature · 2017 · 325 citations · Full text

, , +16

Essential role of the posterior morphogen nanos for germline development in Drosophila

Satoru Kobayashi, Masashi Yamada, Miho Asaoka et al. · Nature · 1996 · 305 citations

, , +16

1–5 of 67

Authors

356

  1. MA
    M. Azim Surani

    The Gurdon Institute, United Kingdom

    8 publications · 870 citations

    8

    h-index

  2. TK
    Toshihiro Kobayashi

    The University of Tokyo, Japan

    7 publications · 636 citations

    7

    h-index

  3. NI
    Naoko Irie

    University of Cambridge, United Kingdom

    5 publications · 586 citations

    5

    h-index

  4. MH
    Masumi Hirabayashi

    National Institute for Physiological Sciences, Japan

    3 publications · 155 citations

    3

    h-index

  5. HN
    Hiromitsu Nakauchi

    The University of Tokyo, Japan

    3 publications · 155 citations

    3

    h-index

1–5 of 356

Institutions

120

  1. University of Cambridge

    Cambridge, United Kingdom

    10 h-index

    49 publications

    5.1K citations

  2. Wellcome Trust

    London, United Kingdom

    9 h-index

    37 publications

    4.5K citations

  3. The Gurdon Institute

    Cambridge, United Kingdom

    9 h-index

    39 publications

    4.6K citations

  4. The University of Tokyo

    Tokyo, Japan

    6 h-index

    20 publications

    1.3K citations

  5. Wellcome/MRC Cambridge Stem Cell Institute

    Cambridge, United Kingdom

    6 h-index

    25 publications

    2K citations

  6. National Institute for Physiological Sciences

    Okazaki, Japan

    6 h-index

    14 publications

    722 citations

  7. Kyoto University

    Kyoto, Japan

    5 h-index

    14 publications

    1K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    6 publications

    275 citations

1–8 of 120

Venues

  1. Development

    5 publications · 308 citations

    5

    h-index

  2. PLoS ONE

    5 publications · 151 citations

    5

    h-index

  3. Nature

    4 publications · 2.4K citations

    4

    h-index

  4. Nature Cell Biology

    NCB · 3 publications · 356 citations

    3

    h-index

  5. Biology of Reproduction

    3 publications · 206 citations

    3

    h-index

1–5