Concepedia

Gene Pair Interaction Analysis

Gene Pair Interaction Analysis is a computational method that identifies and characterizes pairs of genes whose combined perturbation results in cell lethality, specifically by systematically evaluating epistatic or synthetic lethal interactions between gene pairs to reveal functional dependencies in biological networks.

41

Publications

2K

Citations

189

Authors

108

Institutions

Publications per year

2017–2026

9

Parents

Publications

41

A strategy for extracting and analyzing large-scale quantitative epistatic interaction data

Sean R. Collins, Maya Schuldiner, Nevan J. Krogan et al. · Genome biology · 2006 · 329 citations · Full text

, , +15

Computational analysis of the synergy among multiple interacting genes

Dimitris Anastassiou · Molecular Systems Biology · 2007 · 202 citations · Full text

, , +12

A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes

Andy Lin, Richard T. Wang, Sangtae Ahn et al. · Genome Research · 2010 · 128 citations · Full text

, , +17

Gene interaction and single gene effects in colon tumour susceptibility in mice

Tom van Wezel, Alphons P. M. Stassen, Corina J.A. Moen et al. · Nature Genetics · 1996 · 127 citations

, , +15

Genome-Wide Interaction-Based Association Analysis Identified Multiple New Susceptibility Loci for Common Diseases

Yang Liu, Haiming Xu, Suchao Chen et al. · PLoS Genetics · 2011 · 91 citations · Full text

, , +13

1–5 of 41

Authors

189

  1. MS
    Matthew Schultz

    Allegheny-Singer Research Institute, United States

    1 publications · 41 citations

    1

    h-index

  2. DS
    Desmond Smith

    University of California, Los Angeles, United States

    1 publications · 128 citations

    1

    h-index

  3. JK
    Jeongwoo Kim

    Yonsei University, South Korea

    1 publications · 18 citations

    1

    h-index

  4. AP
    Aki P. Järvinen

    University of Turku, Finland

    1 publications · 11 citations

    1

    h-index

  5. SS
    Sheng-Hsiung Sheu

    Kaohsiung Medical University Chung-Ho Memorial Hospital, Taiwan

    1 publications · 67 citations

    1

    h-index

1–5 of 189

Institutions

108

  1. Max Planck Society

    Munich, Germany

    2 h-index

    4 publications

    126 citations

  2. University of California San Diego

    San Diego, United States

    2 h-index

    5 publications

    205 citations

  3. Kyoto University

    Kyoto, Japan

    2 h-index

    6 publications

    128 citations

  4. University of Minnesota

    Minneapolis, United States

    2 h-index

    6 publications

    288 citations

  5. University of Southern California

    Los Angeles, United States

    2 h-index

    4 publications

    278 citations

  6. Harvard University

    Cambridge, United States

    2 h-index

    2 publications

    51 citations

  7. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    6 publications

    465 citations

  8. Massachusetts General Hospital

    Boston, United States

    1 h-index

    1 publications

    41 citations

1–8 of 108

Venues

  1. PLoS ONE

    8 publications · 224 citations

    8

    h-index

  2. Bioinformatics

    6 publications · 174 citations

    6

    h-index

  3. BMC Bioinformatics

    3 publications · 117 citations

    3

    h-index

  4. Genome biology

    2 publications · 396 citations

    2

    h-index

  5. PLoS Computational Biology

    2 publications · 97 citations

    2

    h-index

1–5