Concepedia

Gene Knockout Analysis

Gene Knockout Analysis is a functional genomics method that involves the targeted disruption or deletion of a specific gene to determine its biological role by observing the resulting phenotypic changes in the organism.

45

Publications

2.8K

Citations

284

Authors

99

Institutions

Publications per year

2017–2026

16

Parents

Publications

45

Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects

Joshua M. Dempster, Isabella Boyle, Francisca Vázquez et al. · Genome biology · 2021 · 411 citations · Full text

, , +14

Multiple knockout analysis of genetic robustness in the yeast metabolic network

David Deutscher, Isaac Meilijson, Martin Kupiec et al. · Nature Genetics · 2006 · 200 citations

, , +16

The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines

Alshad S. Lalani, Kathryn Graham, Karen Mossman et al. · Journal of Virology · 1997 · 178 citations · Full text

, , +17

Systematic phenome analysis of Escherichia coli multiple‐knockout mutants reveals hidden reactions in central carbon metabolism

Kenji Nakahigashi, Yoshihiro Toya, Nobuyoshi Ishii et al. · Molecular Systems Biology · 2009 · 161 citations · Full text

, , +15

Nuclear Factor I X Deficiency Causes Brain Malformation and Severe Skeletal Defects

Katrin Driller, Axel Pagenstecher, Markus Uhl et al. · Molecular and Cellular Biology · 2007 · 142 citations · Full text

, , +12

1–5 of 45

Authors

284

  1. JS
    Jesse S. Boehm

    Broad Institute, United States

    2 publications · 465 citations

    2

    h-index

  2. MK
    Martin Kupiec

    Tel Aviv University, Israel

    2 publications · 222 citations

    2

    h-index

  3. FV
    Francisca Vázquez

    Dana-Farber Cancer Institute, United States

    2 publications · 465 citations

    2

    h-index

  4. IB
    Isabella Boyle

    Broad Institute, United States

    2 publications · 465 citations

    2

    h-index

  5. JM
    Joshua M. Dempster

    Broad Institute, United States

    2 publications · 465 citations

    2

    h-index

1–5 of 284

Institutions

99

  1. Canada's Michael Smith Genome Sciences Centre

    Vancouver, Canada

    2 h-index

    8 publications

    380 citations

  2. Tel Aviv University

    Tel Aviv, Israel

    2 h-index

    6 publications

    844 citations

  3. Broad Institute

    Cambridge, United States

    2 h-index

    16 publications

    3.7K citations

  4. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    7 publications

    226 citations

  5. Dana-Farber Cancer Institute

    Boston, United States

    2 h-index

    2 publications

    465 citations

  6. University of British Columbia

    Vancouver, Canada

    2 h-index

    9 publications

    412 citations

  7. Macquarie University

    Sydney, Australia

    2 h-index

    3 publications

    193 citations

  8. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    5 publications

    166 citations

1–8 of 99

Venues

  1. Applied and Environmental Microbiology

    AEM · 4 publications · 184 citations

    4

    h-index

  2. Scientific Reports

    2 publications · 87 citations

    2

    h-index

  3. PLoS Computational Biology

    1 publications · 28 citations

    1

    h-index

  4. Nature Genetics

    1 publications · 200 citations

    1

    h-index

  5. Molecular and Cellular Biology

    MCB · 1 publications · 142 citations

    1

    h-index

1–5