Concepedia

Fructose Metabolism

Fructose Metabolism is a specialized pathway of carbohydrate metabolism in which dietary fructose is enzymatically converted—predominantly in the liver via fructokinase and aldolase B, and to a lesser extent in extrahepatic tissues via hexokinase—into triose phosphate intermediates that bypass the phosphofructokinase-1 regulatory step and feed into glycolysis, gluconeogenesis, glycogenesis, and lipogenesis for energy production and carbon storage.

3.9K

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189.2K

Citations

12.9K

Authors

2.6K

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Publications per year

2017–2026

517

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Children

Publications

3.9K

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

Kimber L. Stanhope, Jean Marc Schwarz, Nancy L. Keim et al. · Journal of Clinical Investigation · 2009 · 1.7K citations · Full text

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A causal role for uric acid in fructose-induced metabolic syndrome

Takahiko Nakagawa, Hanbo Hu, Sergey Zharikov et al. · American Journal of Physiology-Renal Physiology · 2005 · 1.1K citations

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Fructose-induced insulin resistance and hypertension in rats.

In‐Sul Hwang, Helen Ho, Brian B. Hoffman et al. · Hypertension · 1987 · 890 citations

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Fructose consumption as a risk factor for non-alcoholic fatty liver disease

Xiaosen Ouyang, Pietro Cirillo, Yuri Y. Sautin et al. · Journal of Hepatology · 2008 · 859 citations · Full text

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Correction: Corrigendum: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

Miguel A. Lanaspa, Takuji Ishimoto, Nanxing Li et al. · Nature Communications · 2013 · 798 citations · Full text

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Authors

12.9K

  1. RJ
    Richard J. Johnson

    University of Colorado Denver, United States

    42 publications · 7.9K citations

    31

    h-index

  2. EV
    Emile Van Schaftingen

    UCLouvain, Belgium

    35 publications · 2.7K citations

    27

    h-index

  3. LT
    Luc Tappy

    University of Lausanne, Switzerland

    38 publications · 2.7K citations

    26

    h-index

  4. SP
    S. Pontremoli

    University of Genoa, Italy

    36 publications · 1.5K citations

    22

    h-index

  5. HG
    H G Hers

    UCLouvain, Belgium

    28 publications · 2.7K citations

    22

    h-index

1–5 of 12.9K

Institutions

2.6K

  1. UCLouvain

    Louvain-la-Neuve, Belgium

    29 h-index

    122 publications

    6.8K citations

  2. University of Colorado Denver

    Denver, United States

    29 h-index

    211 publications

    32.4K citations

  3. Harvard University

    Cambridge, United States

    27 h-index

    116 publications

    9.8K citations

  4. University of Lausanne

    Lausanne, Switzerland

    26 h-index

    168 publications

    12.8K citations

  5. University of California, Davis

    Davis, United States

    26 h-index

    130 publications

    25.8K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    175 publications

    6.3K citations

  7. Vanderbilt University

    Nashville, United States

    25 h-index

    133 publications

    8.7K citations

  8. University of Oxford

    Oxford, United Kingdom

    25 h-index

    96 publications

    7.7K citations

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Venues

  1. Journal of Biological Chemistry

    JBC · 141 publications · 9.5K citations

    57

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  2. Journal of Bacteriology

    JB · 97 publications · 4.7K citations

    43

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  3. American Journal of Clinical Nutrition

    AJCN · 51 publications · 4.8K citations

    37

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  4. PubMed

    Repository · 148 publications · 5.3K citations

    36

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  5. Biochemical Journal

    BJ · 71 publications · 3.8K citations

    36

    h-index

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