Concepedia

Foxn1 Function

Foxn1 Function is a molecular genetic mechanism, specifically a transcription factor activity, that governs thymic epithelial cell differentiation and thymus organogenesis during embryonic development.

98

Publications

5.6K

Citations

616

Authors

231

Institutions

Publications per year

2017–2026

33

Parents

Publications

98

Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice

Gina Balc̆iūnaite, Marcel P. Keller, Egle Balciunaite et al. · Nature Immunology · 2002 · 265 citations

, , +9

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

Lizhen Chen, Shiyun Xiao, Nancy R. Manley · Blood · 2008 · 223 citations · Full text

, , +7

Regeneration of the aged thymus by a single transcription factor

Nicholas Bredenkamp, Craig S. Nowell, Clare Blackburn · Development · 2014 · 193 citations · Full text

, , +17

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

Saulius Žuklys, Adam E. Handel, Saule Zhanybekova et al. · Nature Immunology · 2016 · 189 citations · Full text

, , +15

An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

Nicholas Bredenkamp, Svetlana Ulyanchenko, Kathy E. O’Neill et al. · Nature Cell Biology · 2014 · 176 citations · Full text

, , +14

1–5 of 98

Authors

616

  1. BG
    Barbara Gawrońska‐Kozak

    InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Poland

    9 publications · 287 citations

    9

    h-index

  2. CP
    Claudio Pignata

    Federico II University Hospital, Italy

    8 publications · 454 citations

    8

    h-index

  3. MK
    Marta Kopcewicz

    Polish Academy of Sciences, Poland

    8 publications · 218 citations

    8

    h-index

  4. GA
    Georg A. Holländer

    University Children’s Hospital Basel, Switzerland

    8 publications · 651 citations

    8

    h-index

  5. NR
    Nancy R. Manley

    University of Georgia, United States

    7 publications · 797 citations

    7

    h-index

1–5 of 616

Institutions

231

  1. Polish Academy of Sciences

    Warsaw, Poland

    9 h-index

    41 publications

    1.1K citations

  2. InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences

    Olsztyn, Poland

    9 h-index

    41 publications

    1.1K citations

  3. University Children’s Hospital Basel

    Basel, Switzerland

    8 h-index

    19 publications

    2.1K citations

  4. University of Georgia

    Athens, United States

    8 h-index

    20 publications

    1.9K citations

  5. Max Planck Institute of Immunobiology and Epigenetics

    Freiburg, Germany

    8 h-index

    26 publications

    1.9K citations

  6. University of Edinburgh

    Edinburgh, United Kingdom

    7 h-index

    34 publications

    4K citations

  7. University of Basel

    Basel, Switzerland

    7 h-index

    22 publications

    3.3K citations

  8. Federico II University Hospital

    Naples, Italy

    7 h-index

    29 publications

    1.4K citations

1–8 of 231

Venues

  1. PLoS ONE

    8 publications · 267 citations

    8

    h-index

  2. The Journal of Immunology

    JI · 7 publications · 459 citations

    7

    h-index

  3. Scientific Reports

    5 publications · 162 citations

    5

    h-index

  4. Blood

    4 publications · 506 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 248 citations

    3

    h-index

1–5