Concepedia

Extrahepatic Clearance

Extrahepatic Clearance is the metabolic clearance of a substance occurring in tissues outside the liver, distinguishing it from hepatic clearance mechanisms.

106

Publications

6K

Citations

552

Authors

142

Institutions

Publications per year

2017–2026

12

Parents

Publications

106

Differential Induction of Prehepatic and Hepatic Metabolism of Verapamil by Rifampin

Martin F. Fromm, Dagmar Busse, H. Kroemer et al. · Hepatology · 1996 · 281 citations · Full text

, , +17

Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor.

Tomoko Kita, J L Goldstein, Matthew S. Brown et al. · Proceedings of the National Academy of Sciences · 1982 · 261 citations · Full text

, , +15

Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates

Kirk Brown, Jayaprakash K. Nair, Maja M. Janas et al. · Nature Biotechnology · 2022 · 245 citations

, , +16

Extrahepatic Metabolism of Drugs and other Foreign Compounds

John A. Timbrell · Biochemical Society Transactions · 1981 · 232 citations

, , +14

In Vitro Analysis of Human Drug Glucuronidation and Prediction of in Vivo Metabolic Clearance

Matthew G. Soars, Brian Burchell, Robert J. Riley · Journal of Pharmacology and Experimental Therapeutics · 2002 · 228 citations

, , +17

1–5 of 106

Authors

552

  1. DP
    David Polidori

    Janssen (United States), United States

    4 publications · 263 citations

    4

    h-index

  2. EB
    Eric Burak

    Guilford College, United States

    2 publications · 31 citations

    2

    h-index

  3. HH
    Haruhiko Hiraoka

    Gunma University, Japan

    2 publications · 215 citations

    2

    h-index

  4. RN
    Richard N. Bergman

    University of Southern California, United States

    2 publications · 102 citations

    2

    h-index

  5. LM
    Lucy M. Anderson

    National Cancer Institute, United States

    2 publications · 31 citations

    2

    h-index

1–5 of 552

Institutions

142

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    6 h-index

    14 publications

    987 citations

  2. Vanderbilt University

    Nashville, United States

    4 h-index

    14 publications

    483 citations

  3. Janssen (United States)

    Hopewell, United States

    4 h-index

    4 publications

    263 citations

  4. University of Washington

    Seattle, United States

    4 h-index

    14 publications

    1.3K citations

  5. University of Groningen

    Groningen, The Netherlands

    3 h-index

    16 publications

    464 citations

  6. Cedars-Sinai Medical Center

    Los Angeles, United States

    3 h-index

    5 publications

    299 citations

  7. Pfizer (United States)

    New York, United States

    3 h-index

    33 publications

    2.2K citations

  8. University of Minnesota

    Minneapolis, United States

    2 h-index

    8 publications

    80 citations

1–8 of 142

Venues

  1. Drug Metabolism and Disposition

    10 publications · 304 citations

    10

    h-index

  2. Journal of Clinical Investigation

    JCI · 5 publications · 617 citations

    5

    h-index

  3. PubMed

    Repository · 5 publications · 134 citations

    5

    h-index

  4. Hepatology

    5 publications · 342 citations

    5

    h-index

  5. Biochemical Pharmacology

    5 publications · 316 citations

    5

    h-index

1–5