Concepedia

Expression Quantitative Trait Locus Fine-mapping

Expression Quantitative Trait Locus Fine-Mapping is a statistical genomic method that refines the identification of causal genetic variants underlying gene expression variation by integrating association signals with functional genomic annotations and linkage disequilibrium patterns to prioritize likely causal single nucleotide polymorphisms within expression quantitative trait loci regions.

42

Publications

3.2K

Citations

1.5K

Authors

223

Institutions

Publications per year

2017–2026

21

Variants

Eqtl Fine-mapping

Parents

Publications

42

Chromatin marks identify critical cell types for fine mapping complex trait variants

Gosia Trynka, Cynthia Sandor, Buhm Han et al. · Nature Genetics · 2012 · 669 citations

, , +16

Probabilistic fine-mapping of transcriptome-wide association studies

Nicholas Mancuso, Malika Freund, Ruth Johnson et al. · Nature Genetics · 2019 · 444 citations · Full text

, , +13

Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue

Federico Innocenti, Gregory M. Cooper, Ian B. Stanaway et al. · PLoS Genetics · 2011 · 210 citations · Full text

, , +17

A practical view of fine-mapping and gene prioritization in the post-genome-wide association era

Roeland Broekema, Olivier B. Bakker, Iris H. Jonkers · Open Biology · 2020 · 135 citations · Full text

, , +17

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

Christopher M. Vockley, Cong Guo, William H. Majoros et al. · Genome Research · 2015 · 119 citations · Full text

, , +17

1–5 of 42

Authors

1.5K

  1. EE
    Eleazar Eskin

    University of California, Los Angeles, United States

    3 publications · 125 citations

    3

    h-index

  2. XW
    Xiaoquan Wen

    University of Michigan, United States

    3 publications · 231 citations

    3

    h-index

  3. AJ
    Aldons J. Lusis

    University of California, Los Angeles, United States

    3 publications · 94 citations

    3

    h-index

  4. PK
    Peter Kraft

    Harvard University, United States

    3 publications · 127 citations

    3

    h-index

  5. SE
    Stephane E. Castel

    New York Genome Center, United States

    2 publications · 111 citations

    2

    h-index

1–5 of 1.5K

Institutions

223

  1. Harvard University

    Cambridge, United States

    9 h-index

    20 publications

    4K citations

  2. University of California, Los Angeles

    Los Angeles, United States

    7 h-index

    33 publications

    4K citations

  3. University of Michigan

    Ann Arbor, United States

    7 h-index

    7 publications

    335 citations

  4. University of Chicago

    Chicago, United States

    6 h-index

    41 publications

    4.1K citations

  5. Broad Institute

    Cambridge, United States

    6 h-index

    25 publications

    4.5K citations

  6. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    8 publications

    2.1K citations

  7. University of Washington

    Seattle, United States

    4 h-index

    13 publications

    1.9K citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    10 publications

    724 citations

1–8 of 223

Venues

  1. PLoS Genetics

    4 publications · 413 citations

    4

    h-index

  2. Genetics

    4 publications · 250 citations

    4

    h-index

  3. Nature Genetics

    3 publications · 1.2K citations

    3

    h-index

  4. Human Genetics

    2 publications · 56 citations

    2

    h-index

  5. Human Molecular Genetics

    2 publications · 115 citations

    2

    h-index

1–5