Concepedia

Enzyme Oligomerization

Enzyme Oligomerization is the process by which multiple enzyme subunits associate through non-covalent interactions to form a functional oligomeric complex, distinguishing it from monomeric enzymes by enabling cooperative regulation, enhanced stability, and allosteric control in metabolic pathways.

190

Publications

9.4K

Citations

851

Authors

296

Institutions

Publications per year

2017–2026

34

Parents

Publications

190

Stabilization of multimeric enzymes: Strategies to prevent subunit dissociation

Roberto Fernández‐Lafuente · Enzyme and Microbial Technology · 2009 · 616 citations

, , +14

Cytochrome c and dATP-mediated Oligomerization of Apaf-1 Is a Prerequisite for Procaspase-9 Activation

Ayman Saleh, Srinivasa M. Srinivasula, Samir Acharya et al. · Journal of Biological Chemistry · 1999 · 503 citations · Full text

, , +16

Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments

Joelle N. Pelletier, François‐Xavier Campbell‐Valois, Stephen W. Michnick · Proceedings of the National Academy of Sciences · 1998 · 386 citations

, , +17

WD-40 Repeat Region Regulates Apaf-1 Self-association and Procaspase-9 Activation

Yuanming Hu, David M. Spencer, Gabriel Núñez · Journal of Biological Chemistry · 1998 · 255 citations · Full text

, , +16

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL–PDGFRβ oncoprotein

C. Jousset · The EMBO Journal · 1997 · 216 citations · Full text

, , +9

1–5 of 190

Authors

851

  1. AS
    Avigdor Shafferman

    Israel Institute for Biological Research, Israel

    3 publications · 115 citations

    3

    h-index

  2. CK
    Chad K. Park

    University of Arizona, United States

    3 publications · 37 citations

    3

    h-index

  3. NC
    Nancy C. Horton

    University of Arizona, United States

    3 publications · 37 citations

    3

    h-index

  4. RJ
    Rainer Jaenicke

    University of Regensburg, Germany

    3 publications · 105 citations

    3

    h-index

  5. JL
    Jonathan L. Sanchez

    University of Arizona, United States

    3 publications · 37 citations

    3

    h-index

1–5 of 851

Institutions

296

  1. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    22 publications

    1.7K citations

  2. University of Regensburg

    Regensburg, Germany

    6 h-index

    19 publications

    429 citations

  3. University of California, Berkeley

    Berkeley, United States

    5 h-index

    15 publications

    571 citations

  4. University of Basel

    Basel, Switzerland

    4 h-index

    6 publications

    655 citations

  5. Umeå University

    Umeå, Sweden

    4 h-index

    10 publications

    675 citations

  6. Japan Science and Technology Agency

    Tokyo, Japan

    4 h-index

    6 publications

    193 citations

  7. ETH Zurich

    Zurich, Switzerland

    4 h-index

    14 publications

    559 citations

  8. University of Groningen

    Groningen, The Netherlands

    4 h-index

    20 publications

    714 citations

1–8 of 296

Venues

  1. Journal of Biological Chemistry

    JBC · 24 publications · 2.1K citations

    19

    h-index

  2. Biochemistry

    15 publications · 442 citations

    13

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.1K citations

    12

    h-index

  4. Journal of Molecular Biology

    JMB · 9 publications · 413 citations

    9

    h-index

  5. Biochemical Journal

    BJ · 6 publications · 234 citations

    6

    h-index

1–5